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Seronegative and Low Seropositive Treatment-Naive Secondary Syphilis in India: A Cross Sectional Study.
Indian J Dermatol
October 2024
From the Department of Dermatology, Venereology and Leprosy, KPC Medical College and Hospital, Kolkata, West Bengal, India.
The non-treponemal tests like VDRL and RPR hold an important place in the diagnosis of syphilis. In many countries, these tests are used for screening, with positive results being subsequently confirmed by treponemal or specific tests like TPHA or FTA-ABS. Recent observations of low-titer VDRL or RPR positivity (<1:8) or negative results in patients with clinically active syphilis are becoming a cause for concern especially in the backdrop of a resurgence of the disease.
View Article and Find Full Text PDFSyphilitic hepatitis in infants, the forgotten disease that hepatologists have to brush up on: from a case series to a revision of literature.
Eur J Pediatr
November 2024
Pediatric Department for the Treatment and Study of Abdominal Diseases and Abdominal Transplantation, IRCCS ISMETT (Mediterranean Institute for Transplantation and Advanced Specialized Therapies), University of Pittsburgh Medical Center, 90127, Palermo, Italy.
Clinical manifestations of congenital syphilis (CS) include liver disease with/without impaired liver function, identified as syphilitic hepatitis. Hepatic involvement may be dramatic; therefore, early diagnosis is crucial to provide treatment and prevent fatal outcomes. A new resurgence of CS cases has been described in recent years worldwide.
View Article and Find Full Text PDFEfficacy of Voluntary Medical Male Circumcision to Prevent HIV Infection Among Men Who Have Sex With Men : A Randomized Controlled Trial.
Ann Intern Med
June 2024
School of Public Health, Fudan University, Shanghai, China, and Shenzhen Campus, Sun Yat-sen University, Shenzhen, China (H.Z.).
Background: Observational studies suggest that voluntary medical male circumcision (VMMC) may lower HIV risk among men who have sex with men (MSM). A randomized controlled trial (RCT) is needed to confirm this.
Objective: To assess the efficacy of VMMC in preventing incident HIV infection among MSM.
Demographics of Youth With Newly Diagnosed Acute/Recent HIV Infection in Adolescent Trials Network 147: Early Treatment of Acute HIV Infection.
J Adolesc Health
March 2024
Department of Pediatrics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.
Purpose: Gay, bisexual, and other cisgender men who have sex with men, and racial minority youth are at elevated risk of acquiring HIV infection. The Adolescent Trials Network 147 recruited youth with acute/recent HIV-infection for early antiretroviral treatment. The cohort make-up is described here.
View Article and Find Full Text PDFPrevalence and Association of Transfusion-Transmissible Infections with Age of Blood Donors: A Regional Transfusion Centre Study in Northern Pakistan.
J Coll Physicians Surg Pak
September 2023
Department of Microbiology, Armed Forces Institute of Transfusion, Rawalpindi, Pakistan.
Objective: To evaluate the prevalence and association of Transfusion-Transmissible Infections (TTIs) with age of blood donors in a regional transfusion centre located in Northern Pakistan.
Study Design: Descriptive study. Place and Duration of the Study: Armed Forces Institute of Transfusion, Rawalpindi, Pakistan, from January 2017 to December 2021.
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