[Preparation and properties of poly (acrylic ester) hydrogel as basic materials for intraocular lens].

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi

The Key Laboratory of Beijing City on Preparation and Processing of Novel Polymer Materials, Material Science and Engineering College, Beijing University of Chemical Technology, Beijing 100029, China.

Published: October 2009

AI Article Synopsis

  • Poly (acrylic ester) hydrogels are popular in intraocular and contact lenses due to their great optical quality and compatibility with the human body.
  • The study explored how varying ratios of hydrophilic (hydroxyethyl methacrylate) and hydrophobic (methyl methacrylate) monomers affect the optical performance, calcium deposits, water content, and overall properties of these hydrogels.
  • Results indicated that increasing the amount of hydrophilic monomer enhanced light transmission and water content while reducing hardness, with the ideal monomer ratio found to be 90% hydrophilic to 10% hydrophobic for optimal performance.

Article Abstract

Poly (acrylic ester) hydrogel materials were widely used in intraocular lens and contact lens because of their excellent optical performance and biocompatibility. In this paper, the bulk copolymerization behavior of hydrophilic hydroxyethyl methacrylat with hydrophobic methyl metharylate was studied; and the optical performance, calcium deposits, equilibrium water content of polymers and its hydrogels obtained by different ratios of monomers were systematically investigated. The experimental results showed that the average light transmittance and the equilibrium water content of the obtained hydrogels increased with the increasing of the hydrophilic monomer content from 0 to 100%; however, the hardness decreased. The highest light transmittance reached 97% and the hardness of Shore A fell from 92 to 25, the equilibrium water content of hydrogel increased from 16% to 64%. The absorbent capacity of copolymers reduced with the adding of cross-linking monomer. When m(hydrophilic monomer): m(hydrophobic monomer) = 90 : 10, the combination property of the polymer and its hydrogel obtained is optimum.

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