Background: The literature provides increasing evidence on how continuing medical education (CME) programs can change provider behavior and improve patient outcomes. Few authors discuss the application of those findings on a relatively common CME activity--grand rounds. Two recent publications about a case study of Medical Grand Rounds provide such an opportunity.
Discussion: Multiple opportunities exist to improve Medical Grand Rounds across each of five evidence-based practices of effective CME: needs assessment, multifaceted intervention strategy, sequencing, interaction, and commitment to change. Planners, presenters, and participants each have a distinct and important role in improving Medical Grand Rounds.
Conclusion: This article identifies important opportunities for planners, presenters, and participants to improve Medical Grand Rounds as a vehicle for changing provider behavior and improving patient outcomes.
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Pathogens
January 2025
Ist Clinic of Obstetrics and Gynecology, "Pius Brinzeu" County Clinical Emergency Hospital, 300723 Timisoara, Romania.
(1) Background: This study aimed to assess the association between inflammatory biomarkers and gastrointestinal side effects in HIV-positive patients on antiretroviral therapy (ART), with a specific focus on the impact of type II diabetes. (2) Methods: A total of 320 participants were divided into three groups: 120 HIV-positive without diabetes, 80 HIV-positive with type II diabetes, and 120 controls. Biomarkers such as CRP, IL-6, and TNF-α, along with gastrointestinal symptoms, were measured before and six months after ART.
View Article and Find Full Text PDFHealthcare (Basel)
January 2025
Northwell Health, Department of Cardiology, 501 Seaview Avenue, Suite 200, Staten Island, NY 10305, USA.
Introduction: Inclisiran is a novel drug that employs ribonucleic acid (RNA) interference to lower the levels of the proprotein convertase subtilisin/kexin type 9 (PCSK9) protein. It has demonstrated a significant reduction in LDL cholesterol levels compared to a placebo. We aim to comprehensively evaluate the safety of using Inclisiran in patients with dyslipidemia and ASCVD or an ASCVD risk equivalent.
View Article and Find Full Text PDFNat Cancer
January 2025
Department of Epigenetics, Van Andel Institute, Grand Rapids, MI, USA.
Mutations in cancer risk genes increase susceptibility, but not all carriers develop cancer. Indeed, while DNA mutations are necessary drivers of cancer, only a small subset of mutated cells go on to cause the disease. To date, the mechanisms underlying individual cancer susceptibility remain unclear.
View Article and Find Full Text PDFEur J Trauma Emerg Surg
January 2025
Department of Surgery, Division of Trauma Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands.
Purpose: The incidence of severely injured older trauma patients is increasing globally, portraying high mortality rates. Exploring the demographics and clinical outcomes of this subgroup is essential to further improve specialised care at the right place. This study was performed to identify severely injured older patients at high risk for mortality by examining their characteristics and identifying prognostic factors contributing to mortality.
View Article and Find Full Text PDFJ Neurol Sci
January 2025
Department of Neurology, University of Michigan, Ann Arbor, MI 48109, USA; NeuroNetwork for Emerging Therapies, University of Michigan, Ann Arbor, MI 48109, USA; Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI 48824, USA. Electronic address:
Objective: Rare neurologic diseases (RNDs) are difficult to diagnose and treat due to their low prevalence and complex nature. This survey evaluated awareness and current care status of RNDs among esteemed neurologists affiliated with the World Federation of Neurology (WFN).
Methods: A 34-question survey was distributed to renowned neurologists, including delegates from national neurology societies in the WFN Assembly, various WFN committees, and members of the Rare Neurologic Diseases Specialist group.
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