[Granulocytic sarcoma, a diagnostic challenge: 3 pediatric cases].

Arch Pediatr

Institut d'hématologie et d'oncologie pédiatrique, 1, place Joseph-Renaut, 69008 Lyon, France.

Published: February 2010

Granulocytic sarcoma (GS) is a rare extramedullary tumor frequently associated with acute myeloblastic leukemia (AML). We report 3 cases of pediatric granulocytic sarcomas with various locations: skin, orbit, and bowel. Cases 1 and 2 were associated with AML; case 3 was isolated. In all 3 cases, the diagnosis was delayed or initially missed. Pathology and immunohistochemistry data identified the disease. GS is treated with chemotherapy, like AML. The prognosis of GS seems better than that of isolated AML.

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http://dx.doi.org/10.1016/j.arcped.2009.10.018DOI Listing

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