Aminocaprophenone- and pyrrolidine-type alkaloids from the leaves of Ficus septica.

J Nat Prod

Biomedicinal Information Research Center, Japan Biological Informatics Consortium, 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan.

Published: December 2009

Two new aminocaprophenone alkaloids, ficuseptamines A (1) and B (2), and a new pyrrolidine alkaloid, ficuseptamine C (3), together with 12 known alkaloids and a known acetophenone derivative were isolated from a methanolic extract of the leaves of Ficus septica. The structures of 1-3 were determined on the basis of their spectroscopic data. The compounds obtained were evaluated for cytotoxicity against two cancer cell lines.

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http://dx.doi.org/10.1021/np900580fDOI Listing

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