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The influence of different factors on biosynthesis of extracellular alpha-amylase of Aspergillus sp. 55 grown at submerged cultivation has been studied. The optimal composition of nutrient medium (1 g of starch and 0.5 g of NaNO3 per 1 l) was chosen. The enzyme preparation has a wide pH optimum of activity (4.5-9.0), thermooptimum at pH 6.5 was 60 degrees C, at pH 4.5 and 9.0--50 degrees C. The inhibitory effect of coordinative germanium compounds on amylolytic activity of the preparation was shown. The paper is presented in Ukrainian.

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