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http://dx.doi.org/10.1007/s12664-009-0051-y | DOI Listing |
J Pharm Pharmacol
October 2024
Department of Pharmacology, Laboratory of Pharmacology Applied to the Gastrointestinal Tract and its Interactions, Federal University of Santa Catarina, Florianópols, Brazil.
Objective: To investigate the effects of Araucaria sp. brown propolis (ABP) against trinitrobenzenesulfonic acid (TNBS)-induced colitis in rats.
Methods: Animals received vehicle (1% DMSO, 1 ml/kg) or hydroalcoholic extract of ABP (hydroalcoholic extract of Araucaria sp.
Arab J Gastroenterol
February 2024
Department of Gastroenterology, Seth GS Medical College and King Edward Memorial Hospital, Acharya Donde Marg, Parel, Mumbai 400012, Maharashtra, India.
Use of Foley catheter in patients with ileostomy, for the decompression of large bowel distal to stoma or for the administration of large bowel enema through colostomy, either to treat constipation or for bowel preparation prior to colonoscopy, is a common practice. Accidental migration of catheter during bowel irrigation through stoma can take place if it is not secured externally to the skin. We present 2 such cases with intra-colonic migration of Foley catheter that occurred during bowel irrigation and were retrieved endoscopically.
View Article and Find Full Text PDFInflamm Bowel Dis
May 2024
Center for Translational Research, Benaroya Research Institute, Seattle, WA, USA.
Background: Vedolizumab, an antibody blocking integrin α4β7, is a safe and effective therapy for Crohn's disease and ulcerative colitis. Blocking α4β7 from binding its cognate addressin MAdCAM-1 on intestinal blood vessel endothelial cells prevents T cells from migrating to the gut mucosa in animal models. However, data supporting this mechanism of action in humans is limited.
View Article and Find Full Text PDFNeurogastroenterol Motil
June 2022
Division of Life Science, Graduate School of Science and Engineering, Saitama University, Saitama, Japan.
Background: The aim of this study was to investigate the fundamental mechanisms of colonic motility in the house musk suncus (Suncus murinus) as an established animal model of gut motility.
Methods: To measure gut motility in free-moving conscious suncus, strain gauge force transducers were implanted on the serosa of the colon and gastric body.
Key Results: We recorded diurnal changes in colonic motility and observed the relationship between feeding and colonic motility.
Surg Innov
October 2019
2 Centre for Surgical Teaching and Research (CERC), Aix-Marseille University, Marseille, France.
. Anastomotic leak is the main complication after low colorectal anastomosis. Defunctioning ileostomy is therefore recommended, which carries its own morbidity.
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