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Mentorship in Otolaryngology Head and Neck Surgery: A Scoping Review.
J Otolaryngol Head Neck Surg
January 2025
Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of British Columbia, Vancouver, BC, Canada.
Importance: Mentorship is increasingly recognized as a critical part of training across the spectrum of trainees. While explored more in-depth in the literature of other medical specialties, mentorship remains a nascent topic in the Otolaryngology Head and Neck Surgery (OHNS) literature.
Objective: The objective of this study was to assess the current literature on mentorship in OHNS.
Dissemination mechanisms of unique antibiotic resistance genes from flowback water to soil revealed by combined Illumina and Nanopore sequencing.
Water Res
December 2024
Key Laboratory of Three Gorges Reservoir Region's Eco-environment, Ministry of Education, Chongqing University, Chongqing 400045, PR China; State Key Laboratory of Coal Mine Disaster Dynamics and Control, Chongqing University, Chongqing 400044, PR China. Electronic address:
As a byproduct of shale gas extraction, flowback water (FW) is produced in large quantities globally. Due to the unique interactions between pollutants and microorganisms, FW always harbor multiple antibiotic resistance genes (ARGs) that have been confirmed in our previous findings, potentially serving as a point source for ARGs released into the environment. However, whether ARGs in FW can disseminate or integrate into the environmental resistome remains unclear.
View Article and Find Full Text PDFInhibition of OATP1B1/3 Rather Than UGT1A1 May Be the Major Cause of the Bilirubin Elevation After Atazanavir Administration.
Clin Pharmacol Ther
December 2024
Department of Pharmaceutical Sciences, Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, California, USA.
Atazanavir has been reported to increase total serum bilirubin level up to ninefold. It is widely believed that the observed total bilirubin elevation is primarily due to UGT1A1 inhibition. However, UGT enzymes are well-known as a low-affinity and high-capacity system, and the observed drug-drug interaction mediated by UGTs is usually less than twofold.
View Article and Find Full Text PDFWhy do healthcare workers refuse tuberculosis preventive treatment (TPT)? a qualitative study from Puducherry, South India.
BMJ Open Respir Res
December 2024
Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
Background: The sustainable development goal (SDG) 3.3.2 prompted India to devise the National Strategic Plan 2017-2025, targeting tuberculosis (TB) eradication by 2030.
View Article and Find Full Text PDFThe selection of target areas for orbital imaging, as well as the application of diethylenetriaminepentaacetic acid orbital imaging, clinical factors, alkaline phosphatase, and thyrotropin receptor antibodies in the staging and grading of thyroid-associated ophthalmopathy, are subjects of research.
Nucl Med Commun
November 2024
Department of Nuclear Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Purpose: This study aimed to investigate whether patients with thyroid-associated ophthalmopathy (TAO) are in the active phase and explore their correlations with various clinical factors, serological tests, and orbital imaging parameters studied. It also aimed to evaluate the diagnostic value of different target areas in orbital imaging for assessing TAO inflammatory activity according to the American NOSPECS classification. Patients were stratified based on their NOSPECS grade to determine statistical differences among different stages.
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