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Chronic wounds are a burden to millions of patients and healthcare providers worldwide. With rising incidence and prevalence, there is an urgent need to address non-healing wounds with novel approaches. Impaired wound healing has been shown to be associated with wound microbiota, and multiple bacterial species are known to contribute to delays in closure.
View Article and Find Full Text PDFAn efficient, high-throughput enrichment system for the rapid detection of E. coli at low concentrations in water.
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School of Ophthalmology & Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, China; Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033, China; University of Chinese Academy of Sciences, Beijing, 100049, China; State Key Laboratory of Applied Optics, Changchun, 130033, China; Key Laboratory of Advanced Manufacturing for Optical Systems, Chinese Academy of Sciences, Changchun, 130033, China. Electronic address:
Certain virulent strains of Escherichia coli (E. coli), notably the enterohemorrhagic serotype O157:H7, are recognized for causing diarrhea, gastroenteritis, and a range of illnesses that pose significant risks to public health and the safety of drinking water supplies. Early detection and management of E.
View Article and Find Full Text PDFUncovering the Role of in Prostate Cancer: Insights from Genetic and Expression Analyses.
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Department of Urology, College of Medicine and Shu-Tien Urological Research Center, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Biochemical recurrence (BCR) is a critical concern in prostate cancer management; however, its underlying genetic determinants remain poorly understood. The () gene family is involved in cellular detoxification and biosynthetic processes and has been implicated in various cancers. This study investigated the association between the family members and prostate cancer recurrence.
View Article and Find Full Text PDFIdentification of significant single-nucleotide polymorphisms associated with breast cancer recurrence and metastasis using GWAS.
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Department of Breast Medical Oncology Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences Jinan Shandong China.
Background: Identification of risk genes and loci associated with the recurrence and metastasis of breast cancer (BC) is of utmost importance. Genome-wide association studies (GWASs) represent valuable tools for identifying the disease risk associated with a given single-nucleotide polymorphism (SNP); they offer significant insights into the disease progression mechanism by analyzing SNP information of the entire genome. Though GWAS has already identified several genetic susceptibility SNPs for BC, their significance in the recurrence and metastasis of this cancer remains unclear.
View Article and Find Full Text PDFSorbent-Based Sampling With Two-Stage Trapping/Desorption Coupled to Comprehensive Two-Dimensional Gas Chromatography and Mass Spectrometry for Terpenoids Profiling in Cannabis.
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Department of Chemical, Pharmaceutical, and Agricultural Sciences University of Ferrara Ferrara Italy.
Cannabis inflorescences represent an important source of many high-value bioactive specialized metabolites, among which the family of terpenes or terpenoids that are the largest classes of natural products known. Besides their biological activities either alone or synergistic with other terpenoids and/or cannabinoids, they are responsible for their distinctive flavour. In this study, we exploited the separation power and identification capabilities of comprehensive two-dimensional gas chromatography coupled to mass spectrometry (GC×GC-MS) for the profiling of terpenes and terpenoids in cannabis inflorescences.
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