The term "multiple eruptive dermatofibromas" usually refers to a clinical situation characterized by the development of between five and eight dermatofibromas during a period of up to four months. It is usually linked to immunodeficiency associated conditions as autoimmune disorders, hematologic malignancies, HIV infection, and transplants. We report three patients with Down syndrome. One patient had psoriatic arthritis under treatment with methotrexate, one had Graves-Basedow disease, and one had hypercholesterolemia. All three patients developed multiple eruptive dermatofibromas. We suggest that the immunologic disturbances associated with Down syndrome, together with other underlying conditions present in these patients, could trigger the development of cutaneous lesions.
Aerosol-producing global catastrophes such as nuclear war, super-volcano eruption, or asteroid strike, although rare, pose a serious threat to human survival. Light-absorbing aerosols would sharply reduce temperature and solar radiation reaching the earth's surface, decreasing crop productivity including for locally adapted traditional crop varieties, i.e.
Syphilis is a sexually acquired disease that can affect multiple organ systems. Secondary syphilis can cause a wide range of skin manifestations, leading to misdiagnoses. Herein, we present a patient who developed a diffuse maculopapular rash concerning for a drug reaction leading to a dermatology consult.
Introduction: Accuracy and user experience of dental diagnosis for a patient with cleidocranial dysplasia (CCD) using immersive virtual reality (VR) and cone-beam computed tomography multiplanar reconstruction methods were evaluated.
Methods: Dental students (n = 40) were randomly assigned to VR or MP groups. VR participants manipulated and visualized the rendered 3-dimensional model using VR hardware and software.
This commentary outlines a novel agenda for future mindfulness research, building on various authors' insights, particularly Indius (Indius, S. (2024). Meditation and Self-transcendence: A Human need? Integrative Psychological and Behavioral Science, 58(3), 878-883), who integrates Maslow's hierarchy of needs into the discussion of mindfulness.
Background: Supernumerary teeth, defined as extra teeth beyond the normal series of dentition, can appear anywhere in the dental arch. They may present as solitary or multiple, unilateral or bilateral, and can be either erupted or impacted. Rarely, supernumerary teeth are found in ectopic locations outside the dental arches, such as the nasal cavity, inferior nasal conchae, maxillary sinus, ethmoid sinus, or skull.
