Introduction And Aims: Qualitative data on local drug scenes in Belgium are scarce. As information on them remains limited to the official registration systems, the needs of a number of drug users are not taken into account. From a social scientific and policy point of view, there is a need for information on the experiences and the patterns of drug use. In this study, we have developed and tested a drugs and alcohol monitor for the city of Antwerp.
Design And Methods: The Antwerp Drugs and Alcohol Monitor (ADAM) combines three qualitative methods: (i) in-depth interviews with 39 key informants; (ii) ethnographic fieldwork by four community fieldworkers; and (iii) ethnographic fieldwork by the researcher. This methodology is based on an analysis of national and international literature on drug-monitoring systems.
Results: This paper presents an overview of the results of a pilot study in the city of Antwerp. The ADAM produces a detailed picture of the local drug issues (nature and extent of use, drug markets, quality of life, etc.) and thus offers the understanding that is required for a well-founded local drug policy.
Discussion And Conclusions: Provided that repeated measurements are made, a local drug monitor can inform policymakers, treatment experts, etc. on developments and phenomena concerning drug use. However, the ADAM is a qualitative drug-monitoring system, and it must be emphasised that a combined monitor is more efficient. Indeed, a combination of qualitative and quantitative methods enhances the reliability of the results.
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http://dx.doi.org/10.1111/j.1465-3362.2009.00061.x | DOI Listing |
Hernia
January 2025
Department of Surgery, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1259, New York, NY, 10029, USA.
Purpose: While surgeons agree that perioperative field blocks should be performed for open inguinal hernia surgery, there lacks consensus in the minimally invasive context. Prior small-scale randomized trials study pain scores only up to 24 h postoperatively. Thus, we sought to investigate the analgesic benefits of a bupivacaine transversus abdominis plane (TAP) block in the first 4 postoperative days.
View Article and Find Full Text PDFEpilepsia
January 2025
Texas Comprehensive Epilepsy Program, Department of Neurosurgery, University of Texas Health Science Center at Houston, Houston, Texas, USA.
Objective: The pulvinar nucleus of the thalamus has extensive cortical connections with the temporal, parietal, and occipital lobes. Deep brain stimulation (DBS) targeting the pulvinar nucleus, therefore, carries the potential for therapeutic benefit in patients with drug-resistant posterior quadrant epilepsy (PQE) and neocortical temporal lobe epilepsy (TLE). Here, we present a single-center experience of patients managed via bilateral DBS of the pulvinar nucleus.
View Article and Find Full Text PDFCancer Rep (Hoboken)
January 2025
Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Background: Denosumab represents a valuable treatment option for unresectable giant cell tumors of the bone (GCTBs). However, no standardized protocols exist determining the length of administration, with few studies having been published on patients who reached the end of treatment.
Aims: To analyze the outcomes of patients diagnosed with GCTB and who had finished single treatment with denosumab.
Expert Opin Drug Deliv
January 2025
Drug Transport and Delivery Research Group, Department of Pharmacy, Faculty of Health Sciences, University of Tromsø The Arctic University of Norway, Tromsø, Norway.
Introduction: Liposomal hydrogels are novel drug delivery systems that comprise preformed liposomes incorporated in hydrogels destined for mostly localized drug therapy, herewith antimicrobial therapy. The formulation benefits from versatility of liposomes as lipid-based nanocarriers that enable delivery of various antimicrobials of different lipophilicities, and secondary vehicle, hydrogel, that assures better retention time of formulation at the infection site. Especially in an era of alarming antimicrobial resistance, efficient localized antimicrobial therapy that avoids systemic exposure of antimicrobial and related side effects is crucial.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Department of Electrical and Computer Systems Engineering, Monash University, Melbourne, VIC 3800, Australia.
Conventional endoscopy is limited in its ability to examine the small bowel and perform long-term monitoring due to the risk of infection and tissue perforation. Wireless Capsule Endoscopy (WCE) is a painless and non-invasive method of examining the body's internal organs using a small camera that is swallowed like a pill. The existing active locomotion technologies do not have a practical localization system to control the capsule's movement within the body.
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