It is experimentally demonstrated that the sesquiterpene lactone leucomisine extracted from Artemisia leucodes exhibits pronounced antibacterial and phagocytosis-stimulating activity.

Download full-text PDF

Source

Publication Analysis

Top Keywords

antibacterial phagocytosis-stimulating
8
[experimental evaluation
4
evaluation antibacterial
4
phagocytosis-stimulating properties
4
properties leucomisine]
4
leucomisine] experimentally
4
experimentally demonstrated
4
demonstrated sesquiterpene
4
sesquiterpene lactone
4
lactone leucomisine
4

Similar Publications

Mucositis is one of the major side effects of anti-cancer therapies. Mucositis may lead to other abnormalities such as depression, infection, and pain, especially in young patients. Although there is no specific treatment for mucositis, several pharmacological and non-pharmacological options are available to prevent its complications.

View Article and Find Full Text PDF

LECT2 Is a Novel Antibacterial Protein in Vertebrates.

J Immunol

April 2022

State Key Laboratory of Agricultural Microbiology, College of Fisheries, Huazhong Agricultural University, Wuhan, China;

In vertebrates, leukocyte-derived chemotaxin-2 (LECT2) is an important immunoregulator with conserved chemotactic and phagocytosis-stimulating activities to leukocytes during bacterial infection. However, whether LECT2 possesses direct antibacterial activity remains unknown. In this article, we show that, unlike tetrapods with a single gene, two genes exist in teleost fish, named and Using grass carp as a research model, we found that the expression pattern of grass carp () is more similar to that of in tetrapods, while has evolved to be highly expressed in mucosal immune organs, including the intestine and skin.

View Article and Find Full Text PDF

It is experimentally demonstrated that the sesquiterpene lactone leucomisine extracted from Artemisia leucodes exhibits pronounced antibacterial and phagocytosis-stimulating activity.

View Article and Find Full Text PDF

Arginine-specific ADP-ribosyltransferase present in granules of chicken polymorphonuclear leukocytes (so-called heterophils) is released into the extracellular space by stimulus of calcium ionophore A23187 or opsonized zymosan [Terashima et al. (1996) J. Biochem.

View Article and Find Full Text PDF

A pilot study with the anti-leprosy agent clofazimine was conducted on seven patients with cheilitis granulomatosa or complete Melkersson-Rosenthal syndrome. Beneficial effects were observed in all patients, dependent on the degree of the clinical expression of the disease: the variable attacks of lip swelling, characteristic for the edematous phase of this disease, were suppressed promptly and completely in all patients. Persistent residual swelling of the lips, caused by cellular inflammatory infiltrates, which was present in four patients prior to therapy, responded much less rapidly and--in three out of four--only incompletely.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!