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Efficacy and Safety of Secondary Surgical Treatment for Refractory Recurrent Corneal Erosion.
Cornea
January 2025
Eyejun Ophthalmic Clinic, Seoul, Republic of Korea; and.
Purpose: To investigate the efficacy and safety of secondary surgical intervention of combined phototherapeutic keratectomy (PTK) with alcohol delamination and peripheral anterior stromal puncture (ASP) for refractory recurrent corneal erosion (RCE).
Methods: This retrospective comparative study defined refractory RCE as cases persisting for more than 6 months after primary surgical intervention. A total of 115 eyes from 115 patients with refractory RCE, treated either with (n = 92) or without (n = 23) the secondary surgical treatment combining PTK and ASP between January 2021 and January 2023, were included.
Stent stoma: Endoscopic stent insertion for refractory small intestine fistulas.
Scand J Surg
January 2025
Interdisciplinary Endoscopy Centre, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.
Background And Aims: The therapeutic management of fistulas presents significant challenges, often involving both conservative and surgical approaches. Despite these interventions, recurrence and postoperative mortality rates remain high. Endoscopic stent insertion into the fistula, along with the creation of a stent stoma, may offer a promising alternative for patients who fail surgical or conservative therapies.
View Article and Find Full Text PDFDrug delivery systems loaded with plant-derived natural products for dental caries prevention and treatment.
J Mater Chem B
January 2025
State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China.
Dental caries, driven by dysbiosis in oral flora and acid accumulation, pose a significant threat to oral health. Traditional methods of managing dental biofilms using broad-spectrum antimicrobials and fluoride face limitations such as microbial resistance. Natural products, with their antimicrobial properties, present a promising solution for managing dental caries, yet their clinical application faces significant challenges, including low bioavailability, variable efficacy, and patient resistance due to sensory properties.
View Article and Find Full Text PDFTherapeutic Dilemmas Arising From a Serpentine Thrombus Across a Patent Foramen Ovale in a Patient With Dilated Cardiomyopathy.
Cureus
December 2024
Cardiology/Internal Medicine, Luton and Dunstable University Hospital, Luton, GBR.
A thrombus straddling a patent foramen ovale (TSPFO) is a rare condition that presents significant health risks, including stroke or myocardial infarction, and can be life-threatening if not promptly addressed. We report the case of a 42-year-old female with morbid obesity who presented with sudden shortness of breath due to a bilateral pulmonary embolism. Imaging revealed a thrombus extending from the right atrium to the left atrium through the patent foramen ovale (PFO).
View Article and Find Full Text PDFAssessment of Malocclusion and Gender Differences in Orthodontic Treatment Needs Among Adolescents Aged 10-13 Years in Eastern India: A Cross-Sectional Study.
Cureus
December 2024
Department of Orthodontics and Dentofacial Orthopedics, Kalinga Institute of Dental Sciences, Kalinga Institute of Industrial Technology (KIIT) Deemed to be University, Bhubaneswar, IND.
Introduction: Malocclusion is a prevalent public health concern among adolescents, impacting both dental health and psychosocial well-being.
Aims And Objectives: To assess the prevalence of orthodontic treatment needs among adolescents aged 10-13 years in Bhubaneswar using the dental health component (DHC) and aesthetic component (AC) of the Index of Orthodontic Treatment Need (IOTN) and to analyze gender-based differences.
Methodology: A cross-sectional study was conducted among 450 school-going children aged 10-13 years using cluster sampling across Bhubaneswar.
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