Woven polydioxanone biodegradable stents: a new treatment option for benign and malignant oesophageal strictures.

Eur Radiol

Department of Radiology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester, M20 4BX, UK.

Published: May 2010

AI Article Synopsis

  • The study involved the use of a new biodegradable esophageal stent for two patients: one with a tough benign esophageal stricture and another needing temporary support during cancer treatment.
  • These stents are delivered using a regular system and allow for better tracking on CT scans, potentially aiding in radiotherapy planning while posing minimal risk of migration.
  • The preliminary results suggest that biodegradable stents could be a promising option for treating difficult esophageal strictures and supporting patients undergoing non-surgical cancer therapies.

Article Abstract

Background: We present our initial experience with a new biodegradable (BD) esophageal stent in two patients, one for a therapy-resistant benign esophageal stricture, and the other as a temporary measure during curative radiotherapy for oesophageal carcinoma.

Methods: The BD stents need to be loaded into a conventional pull-back delivery system but are then placed in a standard fashion. Pre-dilatation should be avoided to reduce the risk of migration, however if migration occurs the stents can be left to dissolve in the stomach. The stents are radiolucent but easily identified on CT with minimal artefact and thus might even aid with radiotherapy planning.

Results: BD stents offer an exciting new strategy for therapy-resistant benign strictures as well as a supportive measure for oesophageal cancer undergoing non-surgical treatment.

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Source
http://dx.doi.org/10.1007/s00330-009-1662-5DOI Listing

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