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STUDY OF DOSE FORMATION FOR THE POPULATION IN RADIOACTIVELY CONTAMINATED AREAS OF ZHYTOMYR REGION BASED ON COMPREHENSIVE RADIATION-HYGIENIC MONITORING.
Probl Radiac Med Radiobiol
December 2024
WHO Country Office in Ukraine, 9B Mykhaila Hrushevskoho Str., Kyiv, 01021, Ukraine.
Objective: the research is to determine the main radiation-hygienic factors influencing the formation of radiation doses among the population of radioactively contaminated territories (RCT) in Zhytomyr region in 2024 and to analyze the dynamics of internal radiation doses based on original experimental studies conducted in reference settlements from 2012 to 2024.
Materials And Methods: In 2024, a comprehensive radiation-hygienic monitoring program was conducted in 11 settlements of Narodychi Territorial Community (TC): the Narodychi and the villages of Selets, Bazar, Rudnya Bazarska, Khrystynivka (Zone 2), Motiyki, Zalissya, Davydky, Radcha, Nova Radcha, and Grezlya (Zone 3). The comprehensive radiation-hygienic monitoring included the following activities: mobile WBC monitoring: 817 measurements (562 adults and 255 children); collection and analysis of food samples: 39 milk samples, 61 potato samples, and 57 samples of wild foods, analyzed for radionuclide content, including 137Cs and 90Sr; assessment of external radiation exposure in these settlements; surveys: 194 individuals were surveyed regarding the consumption volumes of locally produced foods from their own households and purchased foods from commercial networks.
Radiotherapy as a metastasis directed therapy for liver oligometastases - comparative analysis between CT-guided interstitial HDR brachytherapy and two SBRT modalities performed on double-layer and single layer LINACs.
Front Oncol
November 2024
Department of Radiotherapy, Medical University of Lodz, Łódź, Poland.
Introduction: Surgical resection is gold standard for treatment of liver metastasis, locally ablative techniques including computer tomography (CT)-guided interstitial high-dose-rate (HDR) brachytherapy (CT-BRT) and stereotactic body radiotherapy (SBRT) have gained prominence as alternatives, offering comparable outcomes in selected patients. We aim to compare CT-BRT and SBRT - based on dosimetric analysis.
Material And Methods: Patients who underwent CT-BRT for oligometastatic, ≤4cm liver metastases between 2018 and 2024 were eligible.
Technical note: Optimizing spot-scanning proton arc therapy with a novel spot sparsity approach.
Med Phys
November 2024
Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Background: One of the main challenges of utilizing spot-scanning proton arc therapy (SPArc) in routine clinics is treatment delivery efficiency. Spot reduction, which relies on spot sparsity optimization (SSO), is crucial for achieving high delivery efficiency in SPArc.
Purpose: This study aims to develop a novel SSO approach based on the alternating directions method of multipliers (ADMM) for SPArc to achieve high treatment delivery efficiency and maintain optimal dosimetric plan quality.
FLIP: a novel method for patient-specific dose quantification in circulating blood in large vessels during proton or photon external beam radiotherapy treatments.
Phys Med Biol
November 2024
Department of Physics and Applied Mathematics, University of Navarra, Irunlarrea 1, 31008 Pamplona, Spain.
To provide a novel and personalized method (and Irradiation Personalized) using patient-specific circulating blood flows and individualized time-dependent irradiation distributions, to quantify the dose delivered to blood in large vessels during proton or photon external beam radiotherapy.Patient-specific data were obtained from ten cancer patients undergoing radiotherapy, including the blood velocity field in large vessels and the temporal irradiation scheme using photons or protons. The large vessels and the corresponding blood flow velocities are obtained from phase-contrast MRI sequences.
View Article and Find Full Text PDFSelection criteria for circular collimator- vs. Multileaf collimator-based plans in robotic stereotactic radiotherapy for brain metastases and benign intracranial disease: Impact of target size, shape complexity, and proximity to at-risk organs.
Phys Med
November 2024
Department of Neurosurgery, Niigata Neurosurgical Hospital, 3057 Yamada, Nishi-ku, Niigata 950-1101, Japan.
Purpose: This study aimed to determine the selection criteria for circular collimator (CC)- and multileaf collimator (MLC)-based stereotactic radiosurgery (SRS)/stereotactic radiotherapy (SRT) plans for brain metastases (BM) and benign intracranial disease (BID) in terms of geometric parameters using CyberKnife (CK).
Methods: Forty-eight and eighty-five patients with BM and BID, respectively, were included. Two plans using CC and MLC were created for each case.
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