Madelung's disease, or multiple symmetric lipomatosis, is a rare disease, characterized by accumulation of unencapsulated fat, generally located symmetrically around the neck and shoulders. Here, we present the case of a patient with diffuse lipomatosis accompanied by obstructive sleep apnea due to cervical involvement and facial deformity, which made it necessary to use nasal pillows for ventilation. The patient was hospitalized with a diagnosis of pneumonia and required noninvasive ventilation due to severe hypercapnia. A brief review of the literature was made, and we describe and discuss the investigation of this rare clinical case.
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Article Synopsis
- Multiple symmetric lipomatosis (MLS) is a rare metabolic disorder that leads to abnormal fat deposits.
- * It is also referred to as Launois-Bensaude syndrome or Madelung disease.
- * The condition is marked by symmetrical and non-encapsulated fat accumulations in various areas of the body.
A case report on Madelung's disease and comprehensive review of the literature.
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Department of General surgery, Bethune International Peace Hospital, No. 398, Zhongshan West Road, Qiaoxi District, Shijiazhuang, 050051, Hebei Province, China.
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