How cells generate a single axis of polarity for mating, division, and movement is unknown. In this issue, Howell et al. (2009) use a synthetic biology approach to demonstrate that rapid competition for a soluble signaling component (Bem1) is essential to ensure a unique axis of polarity in budding yeast.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812431 | PMC |
http://dx.doi.org/10.1016/j.cell.2009.10.028 | DOI Listing |
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