Compete globally, bud locally.

Cell

Cardiovascular Research Institute and Department of Biochemistry, University of California, San Francisco, San Francisco, CA 94158, USA.

Published: November 2009

How cells generate a single axis of polarity for mating, division, and movement is unknown. In this issue, Howell et al. (2009) use a synthetic biology approach to demonstrate that rapid competition for a soluble signaling component (Bem1) is essential to ensure a unique axis of polarity in budding yeast.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812431PMC
http://dx.doi.org/10.1016/j.cell.2009.10.028DOI Listing

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