Rationale And Objectives: Cavernous malformations (cavernomas) occur in 0.4%-0.9% of the population. The most common symptoms of cavernous malformations are seizures. An improved detection of small cavernomas might possibly help to clarify cryptogenic seizures, which represent 30% of all seizures. The aim of this study was to evaluate the benefit of magnetic resonance imaging at a field strength of 7 T in the detection of cavernomas.

Materials And Methods: Ten consecutive patients with known cavernomas were enrolled in this study. First a T2*-weighted gradient echo sequence was performed at 1.5 T with a slice thickness of 6 mm in axial orientation. Subsequently, the examination was repeated at 7 T. Both examinations were independently read by two blinded senior neuroradiologists. Localization and dimension of the hypointensities were recorded.

Results: One additional hypointensity was detected in one patient, which was not visible in the 1.5 T examination even retrospectively. In another patient with known cavernomatosis, innumerable new small hypointense lesions were detected at 7 T.

Conclusion: Our small series suggests that ultra-high-field magnetic resonance imaging at 7 T improves the detection of cavernomas.

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http://dx.doi.org/10.1016/j.acra.2009.10.001DOI Listing

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