AI Article Synopsis
- The study found a link between specific genetic variations in the IL-1RN and IL-1beta genes and the development of polycystic ovary syndrome (PCOS).
- The presence of allele V in IL-1RN and allele E1 in IL-1beta was associated with a higher risk of developing PCOS.
- These findings suggest that certain genetic factors may contribute to the likelihood of having PCOS.
Article Abstract
The distribution of genotype frequencies, allele frequencies, and haplotype frequencies of variable number of tandem repeats (VNTR) in interleukin (IL) 1RN and IL-1beta (-511C > T, exon-5C.>T) polymorphism demonstrated a positive association with the occurrence of polycystic ovary syndrome (PCOS). The carriage of allele V of IL-1RN and allele E1 of exon-5 on the IL-1beta gene may increase the risk of PCOS.
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| http://dx.doi.org/10.1016/j.fertnstert.2009.09.042 | DOI Listing |
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