Endometriosis and in vitro fertilisation: a review.

Gynecol Endocrinol

Department of OB/GYN and Reproductive Medicine, Faculty of Medicine, University Hospital Arnaud de Villeneuve, INSERM 637, University Montpellier I, 34295 Montpellier cedex 5, France.

Published: November 2009

AI Article Synopsis

  • This review assesses the impact of severe endometriosis on IVF outcomes and explores complications, ovarian stimulation protocols, and the progression of endometrial conditions during treatment.
  • IVF is shown to be an effective infertility treatment for severe endometriosis patients, comparable in success to those without the condition, but carries risks, especially concerning ovarian function.
  • Early initiation of IVF with tailored protocols and thorough patient education about retrieval risks is recommended to optimize treatment results.

Article Abstract

This review aims to evaluate whether severe endometriosis has an impact on the outcome of in vitro fertilisation (IVF), whether IVF is associated with specific complications in this context, whether a specific ovarian stimulation protocol is most appropriate, whether the endometrial condition progresses following ovarian stimulation, and whether endometrial cysts pose a specific problem for IVF. In patients with severe endometriosis, IVF represents an effective treatment option for infertility, as a complement to surgery. The prognostic parameters of IVF are identical to those of other patients. However, the risks related to the severity of endometriosis, particularly the risk of ovarian deficiency, need to be considered. Because of this issue, to which endometriosis-related pain often adds, IVF treatment should be initiated as early as possible, using appropriate protocols and after having fully informed the patient about the specific oocytes retrieval-related risks.

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http://dx.doi.org/10.3109/09513590903159599DOI Listing

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