AI Article Synopsis
- The study focuses on simulating a nanoparticle focusing lens within a microfluidic channel to improve the selection and transfer of biomolecules, addressing challenges in nano and bioengineering.
- An advanced immersed finite element method is used to track the movement of nanoparticles, factoring in Brownian motion and the initial positions of the particles, while treating the fluid flow as an incompressible viscous medium.
- The results show that both moving and stationary nanoparticles can be effectively focused in the channel, suggesting that this numerical method could enhance microfluidic channel design for various applications in biotechnology.
Article Abstract
Lap-on-a-chip system is one of challenging parts in nano and bio engineering fields, for instance, microfluidic channels on the chip are useful for selecting a target particle and mass transferring of boiomolecules in fluid. However, since experimental approach is highly expensive both in time and cost, alternative reliable methods are required to conceive optimized channels. The purpose of this research is to simulate a nanoparticle focusing lens in a microfluidic channel from nanoparticle control point of view. A promising immersed finite element method is expanded to estimate the path of randomly moving nanoparticles through a focusing lens. The channel flow is assumed as incompressible viscous fluid and Brownian motion effects as well as initial position of particle are quantitatively examined. As a representative result, while the nanoparticles with/without Brownian motion were focused along the center of the channel, the concentration factor representing focusing efficiency was calculated. Therefore, it is expected that the newly proposed numerical method considering Brownian motion will be efficiently applicable to design the microfluidic channel containing various particles, molecules and so forth in the near future.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1166/jnn.2009.1787 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Short-term orthokeratology effects on corneal biomechanics with a focus on SPA1 and stress-strain index (SSI) parameters in pediatric myopia.
Arq Bras Oftalmol
January 2025
Department of Ophthalmology, Guangdong Eye Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences. No. 106 Zhongshan Er Road, Guangzhou 510080, China.
Purpose: Although the orthokeratology effects on corneal biomechanics have been proven with clinical trials, reports of stiffness parameter change are scarce. This study investigated the short-term orthokeratology effects in pediatric myopia and compared stiffness parameter changes to those published in recent clinical investigations. This prospective study aimed to investigate corneal biomechanics changes induced by short-term overnight orthokeratology treatment, focusing on stiffness parameter at A1 and stress-strain index.
View Article and Find Full Text PDF"Am I in 'Suboptimal Health'?": The Narratives and Rhetoric in Carving out the Grey Area Between Health and Illness in Everyday Life.
Sociol Health Illn
February 2025
Department of Sociological Studies, The University of Sheffield, Sheffield, UK.
This paper examines the concept of 'suboptimal health' (subhealth, ), a term popularised by traditional Chinese medicine (TCM) professionals and widely used in public health discourses in China at the turn of the century. Despite criticisms of it being a commercial buzzword, subhealth provides a unique lens for individuals to articulate their health experiences concerning work and life pressures. Through virtual ethnography on Chinese social media such as Weibo and interviews, this study explores the usage and implications of subhealth in everyday life.
View Article and Find Full Text PDFLensless imaging offers a lightweight, compact alternative to traditional lens-based systems, ideal for exploration in space-constrained environments. However, the absence of a focusing lens and limited lighting in such environments often results in low-light conditions, where the measurements suffer from complex noise interference due to insufficient capture of photons. This study presents a robust reconstruction method for high-quality imaging in low-light scenarios, employing two complementary perspectives: model-driven and data-driven.
View Article and Find Full Text PDFFrom fear to empowerment: the impact of employees AI awareness on workplace well-being - a new insight from the JD-R model.
J Health Organ Manag
January 2025
School of Health and Life Sciences, Teesside University, Middlesbrough, UK.
Purpose: The primary purpose of the study was to explore the impact of health workers' awareness of artificial intelligence (AI) on their workplace well-being, addressing a critical gap in the literature. By examining this relationship through the lens of the Job demands-resources (JD-R) model, the study aimed to provide insights into how health workers' perceptions of AI integration in their jobs and careers could influence their informal learning behaviour and, consequently, their overall well-being in the workplace. The study's findings could inform strategies for supporting healthcare workers during technological transformations.
View Article and Find Full Text PDFThe (Im)Material Home: Exploring Older Migrants' Home Experiences Situated within Material and Immaterial Settings of Home. An Exploratory Study in Belgium.
J Cross Cult Gerontol
January 2025
Faculty of Psychology and Educational Sciences, Vrije Universiteit Brussel (VUB), Pleinlaan 2, 1050, Brussels, Belgium.
The older population is diversifying. Extensive research has shown the preference of older adults to age in place. Recent research shows that older migrants also prefer to age in place.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!