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Effect of platelet-rich plasma and platelet-rich fibrin on healing of burn wound with dual-species biofilm.
Kaohsiung J Med Sci
January 2025
Department of Blood Transfusion, General Hospital of Southern Theatre Command of PLA, Guangzhou City, Guangdong Province, China.
This study evaluated the impact of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) on burn wound with dual-species biofilm. Pseudomonas aeruginosa (P. aeruginosa) and Staphylococcus aureus (S.
View Article and Find Full Text PDFMultiple crosslinked, self-healing, and shape-adaptable hydrogel laden with pain-relieving chitosan@borneol nanoparticles for infected burn wound healing.
Theranostics
January 2025
Department of Radiology, Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, Shaanxi, China.
Next-generation wound dressings with multiple biological functions hold promise for addressing the complications and pain associated with burn wounds. A hydrogel wound dressing loaded with a pain-relieving drug was developed for treating infected burn wounds. Polyvinyl alcohol chemically grafted with gallic acid (PVA-GA), sodium alginate chemically grafted with 3-aminobenzeneboronic acid (SA-PBA), Zn, and chitosan-coated borneol nanoparticles with anti-inflammatory and pain-relieving activities were combined to afford a nanoparticle-loaded hydrogel with a PVA-GA/Zn/SA-PBA network crosslinked via multiple physicochemical interactions.
View Article and Find Full Text PDF17q12 microdeletion syndrome.
BMJ Case Rep
November 2024
Department of Pediatrics, All India Institute of Medical Sciences (AIIMS), Mangalagiri, Andhra Pradesh, India
Article Synopsis
- An infant girl developed widespread blisters and skin peeling, along with fever and cough, showing signs of growth and developmental delays.
- Imaging revealed kidney abnormalities, and genetic testing indicated a deletion on chromosome 17 affecting the HNF1B gene.
- Despite the potential diagnosis of Staphylococcal Scalded Skin Syndrome (SSSS), the child was effectively treated with antibiotics, highlighting an unusual case of 17q12 deletion syndrome with early kidney disease and pre-diabetes.
Understanding host's response to staphylococcal scalded skin syndrome.
Acta Paediatr
February 2025
Department of Paediatrics, School of Medicine, University of Crete, Heraklion, Greece.
Aim: The aim of this review was to summarise the current knowledge on host-related factors that contribute to the development and severity of staphylococcal scalded skin syndrome (SSSS) in children.
Methods: A comprehensive assessment and analysis of the existing literature on SSSS clinical features, pathogenesis and susceptibility factors.
Results: SSSS is a blistering skin disease caused by circulating exfoliative toxins (ETs) of Staphylococcus aureus (S.
A new antibacterial with anti-inflammatory properties promotes wound healing through inhibiting cGAS/STING/NF-κB/IRF3 pathway.
Int Immunopharmacol
December 2024
Anhui Province Key Laboratory of Occupational Health, Anhui No.2 Provincial People's Hospital, Hefei 230041, China. Electronic address:
Benzothiazole-urea hybrid 8l was found to be a potent anti-bacterial agent against methicillin-resistant Staphylococcus aureus (MRSA2858) (MIC = 0.78 μM, Eur J Med Chem. 2022,236:114333).
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