Purpose Of Review: Over the past two decades, medicine has seen a robust increase in the use of ventricular assist devices. The purpose of this review is to update the information concerning these devices, their advantages and disadvantages as well as their complications. This is essential, as the demand for these devices is increasing due to the increasing number of patients with end-stage heart failure and limited number of donor hearts available for transplantation.
Recent Findings: First-generation devices consisted of large, cumbersome consoles requiring patient immobilization and often times hospitalization in an ICU setting. Second-generation models focused on patient mobility and discharge from hospital with an improvement in infection rates as well as 1 and 2-year survival rates. Designs for newer devices are focusing on full implantation without percutaneous lines, axial flow mechanisms and patient comfort. Additionally, total artificial hearts are being designed for the treatment of biventricular failure. The indications for ventricular assist devices are also being expanded to include destination therapy and alternatives to cardiac transplantation, as the supply of organs continues to be limiting.
Summary: This paper reviews the characteristics, outcomes and design of ventricular assist devices.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1097/ACO.0b013e3283346c83 | DOI Listing |
Rev Esp Anestesiol Reanim (Engl Ed)
January 2025
Departamento de ECMO, Fundación Cardiovascular de Colombia, Floridablanca, Colombia. Electronic address:
Heart failure is a complication that may develop in patients diagnosed with acromegaly. This complication can progress to cardiogenic shock, which in cases like the one described, may be refractory to optimal medical management, necessitating the use of mechanical circulatory support as a bridge to decision. Given the specific morphology of this patient's heart, the likelihood of finding a suitable donor in our environment was very low.
View Article and Find Full Text PDFLife (Basel)
January 2025
Internal Medicine Department, College of Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Background: Heart failure (HF) is a chronic condition that significantly affects morbidity and mortality. For patients with end-stage HF who are not candidates for heart transplantation, left ventricular assist devices (LVADs) provide mechanical circulatory support as a long-term solution, known as destination therapy (DT).
Objective: This meta-analysis aims to synthesize evidence on the survival rates, complications, and quality-of-life improvements associated with LVADs used as destination therapy in patients with end-stage HF.
Diagnostics (Basel)
January 2025
Department of Electrocardiology, Institute of Cardiology, Faculty of Medicine, Jagiellonian University Medical College, 31-008 Kraków, Poland.
Cardiac magnetic resonance (CMR) allows for analysis of cardiac function and myocardial tissue characterization. Increased left ventricular mass (LVM) is an independent predictor of cardiovascular events; however, the diagnosis of left ventricular hypertrophy and its prognostic value strongly depend on the LVM indexation method. Evaluation of the quantity and distribution of late gadolinium enhancement assists in clinical decisions on diagnosis, cardiovascular assessment, and interventions, including the placement of cardiac implantable electronic devices and the choice of an optimal procedural approach.
View Article and Find Full Text PDFJ Neurointerv Surg
January 2025
Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Background: Left ventricular assist devices (LVADs) are used as definitive therapy or as a bridge to heart transplant in patients with advanced heart failure. Thromboembolic complications such as acute ischemic stroke (AIS) are common among patients with LVAD support. This study aims to evaluate the current evidence on the efficacy and safety of mechanical thrombectomy (MT) in patients with AIS due to large vessel occlusions (LVO) and LVAD-support.
View Article and Find Full Text PDFJ Card Fail
January 2025
Columbia University Irving Medical Center, New York, NY. Electronic address:
Background: The benefit of implantable cardioverter-defibrillators (ICD) and cardiovascular resynchronization therapy (CRT-D) in patients supported with a HeartMate 3 left ventricular assist device (LVAD) remains uncertain.
Methods: An analysis of the MOMENTUM 3 randomized clinical trial and the first 1000 patients in the Continued Access Protocol trial. Patients were divided into three groups based on the presence of ICD and/or CRT-D: No device (n=153, 11%), ICD only (n=699, 50.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!