Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Access to high-fat diet results in increased sensitivity to the psychostimulant effects of MDPV in mice.
Pharmacol Rep
January 2025
Research Laboratory CoreLab of the Medical University of Lodz, Łódź, Poland.
Background: The current study investigated the effects of high-fat diet on acute response to 3,4-methylenedioxypyrovalerone (MDPV) in mice. MDPV is a beta-cathinone derivative endowed with psychostimulant activity. Similarly to recreational substances, consumption of palatable food stimulates the mesolimbic dopaminergic system, resulting in neuroadaptive changes.
View Article and Find Full Text PDFcoordinates the IL-10 inducing activity of .
Microbiol Spectr
January 2025
Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Unlabelled: The intestine is home to a complex immune system that is engaged in mutualistic interactions with the microbiome that maintain intestinal homeostasis. A variety of immune-derived anti-inflammatory mediators have been uncovered and shown to be critical for maintaining these beneficial immune-microbiome relationships. Notably, the gut microbiome actively invokes the induction of anti-inflammatory pathways that limit the development of microbiome-targeted inflammatory immune responses.
View Article and Find Full Text PDFRepetitive Transcranial Magnetic Stimulation for the Treatment of Complex Regional Pain Syndrome: A Pilot Study.
J Pain Res
January 2025
School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada.
Purpose: Complex regional pain syndrome (CRPS) is a debilitating chronic pain condition characterized by sensory, motor, and autonomic dysfunction with a world-wide prevalence of 26.2 per 100,000 people per year and is 3 to 4 times more prevalent in females. Repetitive transcranial magnetic stimulation (rTMS) has shown to be beneficial for pain relief in neuropathic pain and initial evidence in CRPS is promising, but studies are limited.
View Article and Find Full Text PDFRegulatory Immune Cell-derived Exosomes: Modes of Action and Therapeutic Potential in Transplantation.
Transplantation
January 2025
Department of Surgery, Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh PA.
Reduced dependence on antirejection agents, improved long-term allograft survival, and induction of operational tolerance remain major unmet needs in organ transplantation due to the limitations of current immunosuppressive therapies. To address this challenge, investigators are exploring the therapeutic potential of adoptively transferred host- or donor-derived regulatory immune cells. Extracellular vesicles of endosomal origin (exosomes) secreted by these cells seem to be important contributors to their immunoregulatory properties.
View Article and Find Full Text PDFAscorbic acid on the induction of salt stress tolerance in guava in the seedling formation phase.
Plant Physiol Biochem
January 2025
Universidade Federal de Campina Grande, Center for Technology and Natural Resources, Campina Grande, 58429-000, Brazil.
Guava is a fruit crop widely exploited in the Northeast region of Brazil. However, its exploitation is limited by water scarcity and, in many cases, producers are forced to use water with high levels of salts in irrigation. Thus, it is necessary to develop techniques to induce plant tolerance to salt stress, and the foliar application of a non-enzymatic compound such as ascorbic acid is a promising alternative to mitigate the deleterious effects on plants.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!