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Ten years of the immunogenetics laboratory performance assessment programme and its impact on the donor and transplant network.
Biomedica
December 2024
Grupo Red de Donación y Trasplantes, Instituto Nacional de Salud, Bogotá, D. C., Colombia.
Introduction. The use of immunological tests before solid organ transplantation is essential to reduce the risk of rejection and post-transplant complications. Therefore, quality control systems in laboratories performing them are necessary for clinical practice.
View Article and Find Full Text PDFA patient with probable rare blood Group B(A) phenotype.
Asian J Transfus Sci
September 2022
Department of Blood Bank, Regency Hospital Limited, Kanpur, Uttar Pradesh, India.
Karl Landsteiner discovered ABO blood group system in the early 20 century, but still, uncertainty remains in immunohematology while detection of ABO subgroups or weaker variants. The presence of weak subgroups in patient samples gives rise to the discrepancy in forward (cell) and reverse (serum) grouping. We here report a case of the B(A) phenotype in a patient who was diagnosed with chronic liver disease with acute pancreatitis, requiring packed red blood cells due to anemia.
View Article and Find Full Text PDFFrom Hero to Zero: A Single Center Retrospective Review of the Utility of Routine Physical Crossmatching.
Am J Transplant
January 2025
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA. Electronic address:
Pre-transplantation HLA antibody testing is necessary to assess compatibility between donor and recipient pairs. Over the past decade, the virtual crossmatch (VXM) has replaced the physical crossmatch (PXM) as the main assessment of pre-transplant histocompatibility. At our center, most transplants have proceeded based solely on the VXM, followed by a retrospective PXM.
View Article and Find Full Text PDFBlood Transfusions for Chronic Malaria Anemia in Prisoners of War on the Thai-Burma Railway 1943-1945.
Am J Trop Med Hyg
January 2025
Australian Defence Force Malaria and Infectious Disease Institute, Enoggera, Australia.
Allied prisoners of war (POWs) working on the Imperial Japanese Army's railroad from Thailand to Burma during 1943-1945 devised a blood transfusion service to rescue severely ill fellow prisoners who were otherwise unlikely to survive the war. Extant transfusion records (1,251 recipients, 1,189 donors) in ledger books held by the United Kingdom National Archives at Kew were accessed and analyzed. Survival to the end of the war in 1945 was determined from Commonwealth War Graves Commission records.
View Article and Find Full Text PDFWeak and partial D phenotyping: a comparison study between molecular and serologic results.
Immunohematology
December 2024
Versiti, Milwaukee, WI.
Variant D antigens can cause variable serologic results when typing with Anti-D reagents. There is limited information regarding the ability of Anti-D reagents to differentiate between D variants defined by genotyping. This study was performed to determine if a panel of 20 U.
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