The course of 357 balloon inflations performed during 38 angioplasties for single-vessel coronary artery disease was prospectively studied using continuous ECG recording. Ischemic ECG changes appeared during 91 percent of the inflations at a mean of 20 +/- 8 seconds after inflation and resolved in 97 percent of those at a mean of 11 +/- 5 seconds after deflation. Elevation of the plasma CPK level was found in six patients who had ischemic ECG changes for at least 7.8 minutes. The duration of ischemia did not exceed 5.4 minutes in any of the patients without CPK elevation. Resolution of the ischemic changes was delayed in patients with CPK elevation and in last vs initial inflations. We conclude that in patients with noninfarcted myocardium, ECG changes follow coronary occlusion and reflow very rapidly, detecting these coronary events with a high sensitivity. Lack of rapid regression predicts lack of reperfusion, and persistence of ischemia for more than 7.8 minutes is sufficient to cause myocardial necrosis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1378/chest.99.2.386 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Assessing outcomes of acute myocarditis in Saudi Arabia: A retrospective tertiary center experience.
Saudi Med J
January 2025
From the College of Medicine (Bin Abdu, Assiri, Altasan, Alghamdi, Alshelawy, Alqahtani, Aljabr, Alnahdi, Alhamzani, Alghamdi, Alzahrani, Alshahrani, Alzahrani, Alshalawi), King Saud Bin Abdulaziz University for Health Sciences; from the Department of Medicine (Bin Abdu, Assiri, Altasan, Alghamdi, Alshelawy, Alqahtani, Aljabr, Alnahdi, Alhamzani, Alghamdi, Alzahrani, Alshahrani, Alzahrani, Alshalawi), King Abdullah International Medical Research Center; and from the Emergency Department (Alshalawi), King Abdulaziz Medical City Riyadh, Kingdom of Saudi Arabia.
Objectives: To assess the clinical course and long-term outcomes of complicated and uncomplicated AM in Saudi Arabia. Acute myocarditis (AM) can have different presentations and outcomes based on different factors, one of which is left ventricular ejection fraction (LVEF).
Methods: Data from 382 patients with suspected AM, admitted between January 2016 and October 2023, were reviewed.
Comparison of P-wave parameter changes after radiofrequency ablation and cryoballoon ablation for paroxysmal atrial fibrillation: An observational cohort study.
J Electrocardiol
January 2025
Department of Cardiology, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK; Department of Cardiovascular Sciences, Clinical Science Wing, University of Leicester, Glenfield Hospital, Leicester, UK; National Institute for Health Research Leicester Research Biomedical Centre, Leicester, UK.
Background: Pulmonary vein isolation (PVI) for paroxysmal atrial fibrillation (PAF) can be performed using one-shot cryoballoon ablation (cryo) or point-by-point radiofrequency ablation (RF). This study compares the changes in P-wave parameters between both ablation methods.
Methods: This single-centre retrospective study included contact force RF and second-generation cryo for PAF between 2018 and 2019.
Data analysis protocol for early autonomic dysfunction characterization after severe traumatic brain injury.
Front Neurol
December 2024
Center for Data Science, Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, United States.
Background: Traumatic brain injury (TBI) disrupts normal brain tissue and functions, leading to high mortality and disability. Severe TBI (sTBI) causes prolonged cognitive, functional, and multi-organ dysfunction. Dysfunction of the autonomic nervous system (ANS) after sTBI can induce abnormalities in multiple organ systems, contributing to cardiovascular dysregulation and increased mortality.
View Article and Find Full Text PDFA Case of Cardiac Resynchronization Therapy for Heart Failure with Reduced Ejection Fraction.
Am J Nurs
December 2024
Nicole Kupchik is an independent clinical nurse specialist at Nicole Kupchik Consulting in Seattle. Sarah Vance is a critical care facility educator at Trident Medical Center in Charleston, SC. Kupchik also coordinates Strip The authors have disclosed no potential conflicts of interest, financial or otherwise.
Editor's note: This is the next installment in a series on electrocardiogram (ECG) interpretation. Nurses in all settings should know the basics, as medications and physiological changes can cause cardiac arrhythmias. Each article will start with a brief case scenario and an ECG strip and then take you step by step through analyzing the heart rhythm.
View Article and Find Full Text PDFThe Prognostic Significance of QTc Prolongation in Lead aVR in Patients with Acute Coronary Syndrome with ST Elevation or Depression.
Medicina (Kaunas)
December 2024
Department of Emergency Medicine, Faculty of Medicine, Gaziantep University, Gaziantep 27410, Turkey.
: In patients with acute coronary syndrome, electrocardiographic parameters, including ST elevation in lead aVR (aVR-STE), ST depression (aVR-STD), and QTc prolongation, are crucial. This study aims to show the predictive value of a longer QTc in emergency department patients with acute coronary syndrome and ≥1 mm ST elevation or depression in the aVR lead in electrocardiography. : A retrospective analysis was conducted on 1273 patients admitted to the emergency department with a preliminary diagnosis of acute coronary syndrome between 2020 and 2023.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!