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Secondary cryofibrinogenemia is related to more severe microangiopathic involvement in systemic sclerosis: results from a retrospective observational study.
Clin Rheumatol
January 2025
Rheumatology Unit, Scleroderma Unit, University Hospital of Modena, Via del Pozzo, 71-41125, Modena, Italy.
The aims of this study were to investigate the prevalence of cryofibrinogenemia in a cohort of patients with systemic sclerosis (SSc) regardless of clinical manifestations, who were admitted to our hospital and determine the associations among CF positivity, disease features and ongoing therapies. This was a monocentric and retrospective study. The inclusion criteria were a diagnosis of SSc (according to the ACR/EULAR 2013 classification criteria), regular administration of i.
View Article and Find Full Text PDFPerianal mass as the debut of metastatic pulmonary neoplasia.
Rev Esp Enferm Dig
January 2025
General and Digestive Surgery. Coloproctology Unit, Hospital Universitario Donostia.
A 56-year-old male smoker presented to the Emergency Department with a painful mass in the left ischiorectal fossa, which had been present for 2 months without any other symptoms. On examination, a hard, violet-colored mass was observed, with an ulcerated central area. Blood tests were normal, and the abdominal-pelvic CT scan showed multiple hypervascular intra-abdominal masses and soft tissue lesions.
View Article and Find Full Text PDFNurse-Led/Involved Home-Based Interventions for Older Adults With Chronic Obstructive Pulmonary Disease (COPD): A Mixed-Methods Systematic Review.
J Clin Nurs
January 2025
School of Nursing and Midwifery College of Health, Medicine, and Wellbeing Hunter and Medical Research Institute Healthcare Transformation Research Program, The Centre for Transformative Nursing, Midwifery, and Health Research, Hunter New England Local Health District, University of Newcastle, Newcastle, New South Wales, Australia.
Aims: To determine the effectiveness of nurse-led/involved home-based interventions for older people with COPD and to explore the experiences of older people and nurses with the interventions.
Design: A mixed-methods systematic review following the JBI methodology for mixed-methods systematic reviews.
Data Sources: The search included relevant and peer-reviewed studies published from January 2010 to December 2023 in CINAHL, MEDLINE, Cochrane Central Register of Controlled Trials, PsycINFO, EMBASE, JBI, EMCARE and ProQuest.
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis.
Cochrane Database Syst Rev
January 2025
Lifespan and Population Health, School of Medicine, University of Nottingham, Nottingham, UK.
Background: Cystic fibrosis is a multisystem disease characterised by the production of thick secretions causing recurrent pulmonary infection, often with unusual bacteria. Intravenous (IV) antibiotics are commonly used in the treatment of acute deteriorations in symptoms (pulmonary exacerbations); however, recently the assumption that exacerbations are due to increases in bacterial burden has been questioned. This is an update of a previously published review.
View Article and Find Full Text PDFPrevalence of Cachexia and Outcomes in Patients With Chronic Diseases: A National Database Analysis of 5 484 103 Hospitalisations.
J Cachexia Sarcopenia Muscle
February 2025
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Background: Cachexia is a frequent companion of chronic diseases and a well-established predictor of poor patient performance and outcome. Since cachexia as a discharge diagnosis is not much investigated, we aimed to investigate prevalence of cachexia in hospitalised patients and their outcome.
Methods: We conducted a retrospective analysis of the National Hospital Health Care Statistics Database using the 10th revision of the International Classification of Diseases codes.
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