Curcumin is a polyphenol responsible for the yellow color of turmeric, a curry spice. A large body of evidence showed that curcumin possessed a variety of beneficial activities. We report a case of transient complete atrioventricular block in a 38-year-old man, after intake of curcumin containing pills for on 1 month. Since all other possible causes of conduction disturbance were excluded and causal relation was achieved by re-intake of the same amount of turmeric containing pills, side-effect of the curcumin containing pills was identified as the most likely diagnosis. After cessation of the pills, no further conduction disturbances and associated symptoms were noticed for the ensuing 6 months since discharge.
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http://dx.doi.org/10.1016/j.ijcard.2009.09.530 | DOI Listing |
Biol Rev Camb Philos Soc
December 2024
Andalusian Interuniversity Institute for Earth System Research (IISTA), Avenida del Mediterráneo, Granada, 18071, Spain.
Plant-plant interactions are major determinants of the dynamics of terrestrial ecosystems. There is a long tradition in the study of these interactions, their mechanisms and their consequences using experimental, observational and theoretical approaches. Empirical studies overwhelmingly focus at the level of species pairs or small sets of species.
View Article and Find Full Text PDFPhysiol Rep
December 2024
Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.
At rest, the menstrual cycle phase impacts ventilation and chemosensitivity. However, during exercise there is inconclusive evidence that the menstrual cycle phase affects ventilation or chemosensitivity. We sought to examine the influence of menstrual phase and hormonal birth control (BC) on chemosensitivity.
View Article and Find Full Text PDFBackground And Objectives: Nonfocal transient neurologic attacks (TNA) have been suggested to increase the risk of stroke, yet the optimal clinical approach of these attacks remains uncertain. We determined whether people who have a nonfocal TNA are at an increased risk of subsequent cardiovascular disease (CVD), akin to the known increased risk of stroke following transient ischemic attack (TIA).
Methods: Within a population-based cohort study among Dutch participants aged 45 years or older, we selected participants who had first-ever TNA, defined as an attack of sudden neurologic symptoms resolving within 24 hours without clear evidence for an alternative diagnosis, during follow-up between 1990 and 2020.
Front Genet
December 2024
Dino Ferrari Center, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Myotonia congenita, both in a dominant (Thomsen disease) and recessive form (Becker disease), is caused by molecular defects in that encodes the major skeletal muscle chloride channel, ClC-1. This channel is important for the normal repolarization of muscle action potentials and consequent relaxation of the muscle, and its dysfunction leads to impaired muscle relaxation after voluntary or evoked contraction and muscle stiffness. More than 300 pathogenic variants have been found in association with congenital myotonia, inherited as recessive or dominant traits (with complete or incomplete penetrance).
View Article and Find Full Text PDFSmall
December 2024
Department of Chemistry, The University of British Columbia, 3247 University Way, Kelowna, BC, V1V 1V7, Canada.
Limitations in solar energy conversion by photocatalysis typically stem from poor underlying charge carrier properties. Transient Absorption (TA) reveals insights on key photocatalytic properties such as charge carrier lifetimes and trapping. However, on the microsecond timescale, these measurements use relatively large probe sizes ranging in millimetres to centimetres which averages the effect of spatial heterogeneity at smaller length scales.
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