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http://dx.doi.org/10.1111/j.1439-0272.2009.01010.x | DOI Listing |
Cell Struct Funct
March 2025
Department of Cell Biology, National Cerebral and Cardiovascular Center Research Institute.
During angiogenesis, sprouting endothelial cells (ECs) migrate and eventually connect to target vessels to form new vessel branches. However, it remains unclear how these sprouting vessels migrate toward the target vessels in three-dimensional space. We performed in vivo imaging of the cerebral capillary network formation in zebrafish to investigate how sprouting tip cells migrate toward their targets.
View Article and Find Full Text PDFBrain Behav Immun
March 2025
Shenzhen-Hong Kong Institute of Brain Science, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, the Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. Electronic address:
In infants, high fever is associated with robust microglial morphological changes, including process retraction and soma enlargement, which contribute to fever-induced seizures. The molecular mechanisms underlying dynamic process retraction during hyperthermia remain poorly understood. Using a hyperthermia-induced microglial activation model in postnatal day 8 mice, we identified the CXCL1-CXCR1 interaction as a key regulator of process retraction.
View Article and Find Full Text PDFJ Neural Eng
March 2025
Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai 200030, P R China, Shanghai, 200240, CHINA.
Machine learning's ability to capture intricate patterns makes it vital in neural engineering research. With its increasing use, ensuring the validity and reproducibility of machine learning methods is critical. Unfortunately, this has not always been the case in practice, as there have been recent retractions across various scientific fields due to the misuse of machine learning methods and validation procedures.
View Article and Find Full Text PDFBlood
March 2025
ASH, Washington, District of Columbia, United States.
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