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Comparison of a rapid antigen test with nucleic acid testing during cocirculation of pandemic influenza A/H1N1 2009 and seasonal influenza A/H3N2. | LitMetric
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Comparison of a rapid antigen test with nucleic acid testing during cocirculation of pandemic influenza A/H1N1 2009 and seasonal influenza A/H3N2.

Jen Kok Christopher C Blyth Hong Foo Jason Patterson Janette Taylor Kenneth McPhie V Mala Ratnamohan Jonathan R Iredell Dominic E Dwyer

J Clin Microbiol

Centre for Infectious Diseases and Microbiology Laboratory Services, Level 3, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales 2145, Australia.

Published: January 2010

The rapid diagnosis of influenza is critical in optimizing clinical management. Rapid antigen tests have decreased sensitivity in detecting pandemic influenza A/H1N1 2009 virus compared to seasonal influenza A subtypes (53.4% versus 74.2%, P < 0.001). Nucleic acid tests should be used to detect pandemic influenza virus when rapid antigen tests are negative.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812250PMC
http://dx.doi.org/10.1128/JCM.01465-09DOI Listing

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