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Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing.
Allergol Select
October 2024
Center for Child and Adolescent Health, Helios Hospital Krefeld, Academic Hospital of RWTH Aachen, Krefeld.
Article Synopsis
- Primary atopic disorders (PAD) are rare genetic conditions caused by specific gene variants that affect skin and immune function, making diagnosis challenging among common allergic disease cases.
- Identifying PAD requires recognizing clinical red flags like family history and unusual infections, as conventional lab tests are inadequate for definitive diagnosis.
- Whole-genome sequencing (WGS) enhances diagnostic efficiency and accuracy, but requires careful interpretation and collaboration among specialists to effectively manage PAD cases.
Single-Stage Arthroscopic Minced Cartilage Implantation for Focal Cartilage Defects of the Glenoid Including Glenolabral Articular Disruption Lesions: A Technical Note.
Arthrosc Tech
September 2024
Department of Shoulder and Elbow Surgery, Schulthess Klinik, Zurich, Switzerland.
Article Synopsis
- Anterior shoulder dislocations are often linked to cartilage defects called GLAD lesions, which are crucial for shoulder stability but frequently overlooked.
- These glenoid cartilage defects can lead to ongoing pain and may result in osteoarthritis, highlighting the need for surgical intervention.
- While traditional methods like prosthetic arthroplasty work for older patients, newer techniques, such as the cost-effective AutoCart procedure, show promise for younger patients by using a simpler one-step process for treating isolated cartilage defects.
Article Synopsis
- The study investigates the effects of injecting satellite myoblasts (SM) and mesenchymal stem cells (MSCs) into rats with chronic rotator cuff (RC) tears to improve muscle recovery and reduce fat degeneration.
- After standardized surgery and treatment, the rats were monitored for 14 weeks to assess the recovery of muscle mass and reduction of adipose tissue in those treated with SM and MSC compared to a control group.
- Results showed that the combination of surgical repair with SM and MSC injections significantly enhanced muscle mass and tendon healing while reducing fat tissue, offering a potential new approach for treating chronic RC injuries.
Body Checking Injuries in National Collegiate Athletic Association Men's Ice Hockey: Findings From the NCAA Injury Surveillance Program 2009/10 to 2019/20.
Clin J Sport Med
November 2024
Datalys Center for Sports Injury Research and Prevention, Indianapolis, Indiana.
Objective: To describe the epidemiology of body checking injuries in the National Collegiate Athletic Association (NCAA) Men's Ice Hockey.
Design: Secondary data analysis of historical cohort data.
Setting: A convenience sample of injuries in NCAA Men's Ice Hockey during the 2009/10 to 2019/20 academic years.
Biomechanical study of 3D-printed titanium alloy pad for repairing glenoid bone defect.
J Orthop Surg (Hong Kong)
May 2024
Department of Orthopedics, Chenggong Hospital of Xiamen University(the 73th Group Military Hospital of People's Liberation Army), Xiamen, China.
The purpose of this study was to investigate the effect of 3D-printed technology to repair glenoid bone defect on shoulder joint stability. The shoulder joints of 25 male cadavers were tested. The 3D-printed glenoid pad was designed and fabricated.
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