A rare clinical condition, herpes Zoster duplex bilateralis, is described. Because the erroneous definition of the disease as a lichen is widespread even in the system of advanced medical training, the importance of differentiation between the notions of herpes and lichen is emphasized.
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Pharmacoeconomics
January 2025
Belgian Health Care Knowledge Centre, Brussels, Belgium.
Background: Forecasting future public pharmaceutical expenditure is a challenge for healthcare payers, particularly owing to the unpredictability of new market introductions and their economic impact. No best-practice forecasting methods have been established so far. The literature distinguishes between the top-down approach, based on historical trends, and the bottom-up approach, using a combination of historical and horizon scanning data.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Clinic of Nuclear Medicine Central University Emergency Military Hospital "Dr Carol Davila", 10825 Bucharest, Romania.
Amyloidosis is a rare pathology characterized by protein deposits in various organs and tissues. Cardiac amyloidosis (CA) can be caused by various protein deposits, but transthyretin amyloidosis (ATTR) and immunoglobulin light chain (AL) are the most frequent pathologies. Protein misfolding can be induced by several factors such as oxidative stress, genetic mutations, aging, chronic inflammation, and neoplastic disorders.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2024
Department of Dermatology, Faculty of Medicine, Firat University, 23200 Elazig, Turkey.
Psoriasis is a chronic, immune-mediated skin disease characterized by lifelong persistence and fluctuating symptoms. The clinical similarities among its subtypes and the diversity of symptoms present challenges in diagnosis. Early diagnosis plays a vital role in preventing the spread of lesions and improving patients' quality of life.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2024
Department of Dermatology, Medical University of Warsaw, 02-006 Warsaw, Poland.
Lichen planus (LP) is a chronic inflammatory disease that can present with significant morbidity, particularly in children. Erosive lichen planus (ELP), its rare destructive subtype, can be particularly difficult to diagnose and manage. We present a rare pediatric case of ELP with multisite involvement and discuss the differential diagnosis.
View Article and Find Full Text PDFIn literate adults, an area along the left posterior fusiform gyrus that is often referred to as the "visual word form area" (VWFA) responds particularly strongly to written characters compared to other visually similar stimuli. Theoretical accounts differ in whether they attribute the strong left-lateralization of the VWFA to a left-hemisphere bias towards visual features used in script, to competition of visual word form processing with that of other visual stimuli processed in the same general cortical territory (especially faces), or to the well-established left-lateralization of the language system.Here we used functional magnetic resonance imaging to test the last hypothesis by investigating lateralization of the VWFA in participants (male and female) who have right-hemisphere language due to a large left-hemisphere perinatal stroke.
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