We report the use of short ultrasonic bursts and high-peak-power laser pulses to detect absorbing objects in thick scattering media (SMs). The detection of ultrasound-tagged photons is performed with a double-pass confocal Fabry-Perot interferometer. Photons shifted by the fundamental and harmonic frequencies of the ultrasonic bursts were observed. Absorbing objects were detected in 30- and 60-mm-thick SMs including a sample of biological tissue.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1364/OL.34.003445 | DOI Listing |
Biomed Opt Express
August 2021
Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.
Optical coherence microscopy (OCM) uses interferometric detection to capture the complex optical field with high sensitivity, which enables computational wavefront retrieval using back-scattered light from the sample. Compared to a conventional wavefront sensor, aberration sensing with OCM via computational adaptive optics (CAO) leverages coherence and confocal gating to obtain signals from the focus with less cross-talk from other depths or transverse locations within the field-of-view. Here, we present an investigation of the performance of CAO-based aberration sensing in simulation, bead phantoms, and mouse brain tissue.
View Article and Find Full Text PDFWe present two versions of a chromatic confocal matrix sensor for the snapshot acquisition of three-dimensional objects. The first version contains separate illumination and detection pinhole arrays, while the second version uses a single pinhole array in double pass. The discrete lateral measurement points defined by the illumination and detection pinhole arrays are evaluated in parallel with a hyperspectral detection module.
View Article and Find Full Text PDFWe present signal-generation models for chromatic confocal imaging systems with illumination and detection pinholes of finite size: a collinear model that considers neither aberrations nor diffraction effects, a geometrical model that accounts for aberrations, and a wave optical model covering both aberrations and diffraction effects. These models are aimed at describing the spectral response of multipoint sensor systems with field-dependent aberrations and vignetting effects. They are suitable for single- and double-pass systems with either diffusely or specularly reflecting surfaces under test.
View Article and Find Full Text PDFAppl Spectrosc
March 2010
Microbeam Molecular Spectroscopy Laboratory, Kansas State University, Manhattan, Kansas, USA.
This reports the first detection of chemical heterogeneity in octenyl succinic anhydride modified single starch granules using a Fourier transform infrared (FT-IR) microspectroscopical technique that combines diffraction-limited infrared microspectroscopy with a step size that is less than the mask projected spot size focused on the plane of the sample. The high spatial resolution was achieved with the combination of the application of a synchrotron infrared source and the confocal image plane masking system of the double-pass single-mask Continuum infrared microscope. Starch from grains such as corn and wheat exists in granules.
View Article and Find Full Text PDFOpt Lett
November 2009
Industrial Materials Institute, National Research Council of Canada, 75 de Mortagne Boulevard, Boucherville, Québec, Canada J4B 6Y4.
We report the use of short ultrasonic bursts and high-peak-power laser pulses to detect absorbing objects in thick scattering media (SMs). The detection of ultrasound-tagged photons is performed with a double-pass confocal Fabry-Perot interferometer. Photons shifted by the fundamental and harmonic frequencies of the ultrasonic bursts were observed.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!