Littoral cell angioma is a rare primary vascular neoplasm of the spleen, composed of littoral cells that line the splenic sinuses of the red pulp. It was thought to be a benign, incidental lesion. However, many recent reports have described it to be a malignant lesion with congenital and immunological associations. The definitive diagnosis can only be made after histology and immunohistochemistry studies.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766879 | PMC |
http://dx.doi.org/10.4103/0971-3026.54886 | DOI Listing |
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