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Venous compression causes chronic cerebral ischaemia in normal pressure hydrocephalus patients.
Fluids Barriers CNS
January 2025
Department of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Background: Cerebral autoregulation is a robust regulatory mechanism that stabilizes cerebral blood flow in response to reduced blood pressure, thereby preventing cerebral ischaemia. Scientists have long believed that cerebral autoregulation also stabilizes cerebral blood flow against increases in intracranial pressure, which is another component that determines cerebral perfusion pressure. However, this idea was inconsistent with the complex pathogenesis of normal pressure hydrocephalus, which includes components of chronic cerebral ischaemia due to mild increases in intracranial pressure.
View Article and Find Full Text PDFHidden Rhythms: A Complex Case of Hyperemesis Gravidarum-Induced Arrhythmias.
Cureus
December 2024
Obstetrics and Gynecology, Cape Fear Valley Medical Center, Fayetteville, USA.
Hyperemesis gravidarum (HG) is a severe condition marked by intense nausea and vomiting during pregnancy, which is different from typical morning sickness. It is marked by weight loss exceeding 5% of pre-pregnancy weight, ketonuria, dehydration, electrolyte imbalances, and in some cases, arrhythmias - primarily linked to electrolyte disturbances. Treatment typically involves conservative measures such as small, bland meals, medications like metoclopramide and ondansetron, and correction of electrolyte abnormalities.
View Article and Find Full Text PDFThe effect of replacing prolonged sitting with intermittent standing during a simulated workday on the subsequent night's sleep.
Sleep Biol Rhythms
January 2025
Department of Epidemiology and Biostatistics, University of West Virginia, Morgantown, WV USA.
A bout of leisure-time physical activity improves sleep on the subsequent night. However, whether breaking up sedentary time during the workday improves sleep is unknown. The purpose of this study was to examine whether breaking up prolonged sitting by standing during the workday leads to better sleep the following night.
View Article and Find Full Text PDFEffects of Long-Term Fasting on Gut Microbiota, Serum Metabolome, and Their Association in Male Adults.
Nutrients
December 2024
State Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing 100094, China.
Background: Long-term fasting demonstrates greater therapeutic potential and broader application prospects in extreme environments than intermittent fasting.
Method: This pilot study of 10-day complete fasting (CF), with a small sample size of 13 volunteers, aimed to investigate the time-series impacts on gut microbiome, serum metabolome, and their interrelationships with biochemical indices.
Results: The results show CF significantly affected gut microbiota diversity, composition, and interspecies interactions, characterized by an expansion of the Proteobacteria phylum (about six-fold) and a decrease in Bacteroidetes (about 50%) and Firmicutes (about 34%) populations.
Syngas Production Improvement from CO2RR Using Cu-Sn Electrodeposited Catalysts.
Materials (Basel)
December 2024
Departamento de Química Física Aplicada, Universidad Autónoma de Madrid (UAM), C/Francisco Tomás y Valiente 7, 28049 Madrid, Spain.
Article Synopsis
- The study explores using electrodeposited copper (Cu) and tin (Sn) in electrocatalysts to efficiently reduce atmospheric CO and produce valuable products while integrating with renewable energy.
- The research focuses on different configurations of Cu and Sn, finding that a catalyst with Sn over a thin layer of Cu performs best, demonstrating promising durability in initial tests.
- Optimized Sn and Cu-based catalysts yield over 60% organic products, mainly CO, at low energy costs (under 3 V), highlighting the process's economic viability.
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