Polyribocytidylate-(3)H-polyriboinosinate (rC-(3)H:rI) enters cultured rabbit kidney cells from the surrounding medium within (1/2) hr after exposure. Grains are found in the cytoplasm, nucleus, and nucleolus. At 2 hr, grains are localized predominantly over the nucleolar regions. Subsequently, the grains in the nucleus become dispersed. A specific receptor site for the initiation of interferon production was not revealed.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225873 | PMC |
| http://dx.doi.org/10.1085/jgp.56.1.99 | DOI Listing |
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