AI Article Synopsis
- The sedimentation constant of hog thyroglobulin is 19.2 x 10^(-13), similar to that of human thyroglobulin.
- The specific volume of hog thyroglobulin is 0.72, with a molecular weight estimated at 700,000 or 650,000 based on different calculations.
- The isoelectric point of native hog thyroglobulin is pH 4.58, while the denatured form has an isoelectric point at pH 5.0, and the molecule itself is not spherical in shape.
Article Abstract
1. The sedimentation constant of hog thyroglobulin is 19.2c10(-13). That of human thyroglobulin is essentially the same. 2. The specific volume of hog thyroglobulin is 0.72. 3. The isoelectric point of native hog thyroglobulin is at pH 4.58, that of denatured thyroglobulin at pH 5.0. 4. The molecular weight of hog thyroglobulin is, in round numbers, 700,000, as calculated from the sedimentation and diffusion constants, or 650,000, as calculated from the sedimentation equilibrium data. 5. The thyroglobulin molecule deviates markedly from the spherical.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141410 | PMC |
| http://dx.doi.org/10.1085/jgp.19.1.95 | DOI Listing |
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