A method for detoxifying Type Z and sp. Newcastle Sh. paradysenteriae (Flexner) has been described. This procedure involves exposing the bacilli at pH 5.0 to 0.01 M periodic acid. Microorganisms treated with this reagent for an appropriate time interval lose approximately 90 per cent of their toxicity, yet they are capable of eliciting in experimental animals antibodies effective against the unaltered organisms.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135711 | PMC |
| http://dx.doi.org/10.1084/jem.85.5.499 | DOI Listing |
Publication Analysis
Top Keywords
periodic acid
8
studies flexner
4
flexner group
4
group dysentery
4
dysentery bacilli
4
bacilli detoxification
4
detoxification shigella
4
shigella paradysenteriae
4
paradysenteriae periodic
4
acid method
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!