AI Article Synopsis
- The chemical extraction of dried and ground type A staphylococci produced a specific protein fraction that has distinct antigenic properties.
- Precipitin tests reveal that this protein reacts strongly with immune sera from organisms that have been exposed to either the whole bacteria or the protein alone, indicating a strong type compatibility.
- Moreover, the type specificity of this protein fraction operates independently from the previously identified type-specific carbohydrate, suggesting different mechanisms of antigen recognition.
Article Abstract
Chemical extraction of lyophilized and ground staphylococci of type A has yielded a type-specific, antigenic fraction which has been shown to be protein. In precipitin tests this fraction reacts in high dilution with homologous immune sera prepared by the injection of animals either with the whole organisms or with the protein itself. Reactions with sera prepared against heterologous types of staphylococci occur only in low dilutions. The type specificity of this fraction has been found to be entirely independent of that of the type-specific carbohydrate described by Julianelle and Wieghard.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135093 | PMC |
| http://dx.doi.org/10.1084/jem.71.5.635 | DOI Listing |
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