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Similar Publications
Cutaneous Changes During Pregnancy: A Comprehensive Review.
Cureus
September 2024
Dermatology, Venereology and Leprosy, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.
Article Synopsis
- Pregnancy leads to significant changes in a woman’s skin, particularly on the face and trunk, due to hormonal, mechanical, and immune factors.
- Common skin alterations during this time include hyperpigmentation, stretch marks, and various vascular changes, along with potential issues like skin tags and other specific conditions.
- Understanding these changes is crucial for healthcare providers to offer proper support and management for expectant mothers, improving clinical care and paving the way for future research.
Eczema herpeticum in an immunocompetent man.
Diagn Microbiol Infect Dis
September 2024
Division of Nephrology, Department of Internal Medicine, Tungs' Taichung Metro Harbor Hospital, Taichung City, Taiwan, R.O.C. Electronic address:
Article Synopsis
- Eczema herpeticum is a serious skin condition caused by the herpes simplex virus, commonly affecting those with weakened immune systems or skin conditions like atopic dermatitis, leading to painful lesions and potential severe complications without proper treatment.
- A case study highlighted a young patient with ankylosing spondylitis, who improved after receiving antiviral and antibiotic treatment, despite not being on immunosuppressive therapy or having a history of related conditions.
- The rise in eczema herpeticum cases is linked to more people with compromised immune systems due to factors like increased HIV/AIDS prevalence, more immunosuppressive treatments, and a rise in atopic dermatitis cases, which can complicate diagnosis due to overlapping symptoms with other conditions like Stevens-John
Generalized Pustular Psoriasis of Pregnancy Successfully Treated With Certolizumab Pegol: A Case Report and Literature Review.
Cureus
May 2024
Center for Dermatology, Allergology and Dermatosurgery, Helios University Hospital Wuppertal, Wuppertal, DEU.
Article Synopsis
- * A case study highlights the effective use of certolizumab pegol, a tumor necrosis factor-alpha inhibitor (TNFi), to manage severe GPPP in a 28-year-old woman.
- * The report includes a review of existing literature on TNFi treatments for GPPP, featuring only 11 documented cases, and discusses the underlying mechanisms of GPPP and why TNFi might be a suitable treatment choice.
Use of biologics in Chinese pregnant patients with deficiency of interleukin-36 receptor antagonist (DITRA): A case series.
Taiwan J Obstet Gynecol
May 2024
Department of Dermatology, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:
Article Synopsis
- Impetigo herpetiformis (IH) is a rare and severe skin condition linked to pregnancy complications, primarily caused by a genetic defect in the IL36RN gene.
- This case series of six Chinese patients with IH during eight pregnancies explored the use of various biologics, like adalimumab, etanercept, and secukinumab, to manage their condition.
- Most patients had successful pregnancies, but one experienced fetal heart rate issues that improved after changing medications, indicating that biologics may be beneficial for treating IH in those with the genetic defect.
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