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Environmental factors inducing gastric cancer: insights into risk and prevention strategies.
Discov Oncol
January 2025
The Second Hospital of Lanzhou University, Lanzhou, 730030, China.
Gastric cancer, a prevalent malignant tumor worldwide, poses a significant challenge to global health. Despite ongoing advancements in treatment methods, its high incidence and mortality rates remain concerning. Although progress in treating gastric cancer is encouraging, a more critical focus is on enhancing prevention efforts.
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Alzheimers Dement
December 2024
College of Medicine, National Taiwan University, Taipei City, Taipei, Taiwan.
Background: The role of diet in modulating inflammation and its potential impact on cognition has raised attention. Additionally, recent research has addressed the disruption of the gut-brain axis in dementia development. This study aims to explore how the interactions between inflammatory diets and Helicobacter pylori (Hp) infection affect cognitive domains in older adults.
View Article and Find Full Text PDFIncreasing miR-1260b predicts the risk of gastric cancer in atrophic gastritis patients and regulates cell growth and metastasis of gastric cancer.
Rev Esp Enferm Dig
January 2025
Rehabilitation Medicine, The Affiliated Hospital of Youjiang Medical University for Nationalities.
Background: Atrophic gastritis is of high risk of progressing to gastric cancer. Screening early gastric cancer and predicting the risk of atrophic gastritis developing into gastric cancer could improve the prognosis of gastric cancer.
Objective: This study evaluated the significance of miR-1260b in early gastric cancer and in the progression of atrophic gastritis to gastric cancer aiming to explore a reliable biomarker.
Global trends and risk factors in gastric cancer: a comprehensive analysis of the Global Burden of Disease Study 2021 and multi-omics data.
Int J Med Sci
January 2025
Medical Oncology Department of Gastrointestinal Cancer, Cancer Hospital of Dalian University of Technology, Liaoning Cancer Hospital & Institute, No.44 Xiaoheyan Road, Dadong District, Shenyang 110042, Liaoning Province, China.
Gastric cancer (GC) remains a significant global health challenge. This study aimed to comprehensively analyze GC epidemiology and risk factors to inform prevention and intervention strategies. We analyzed the Global Burden of Disease Study 2021 data, conducted 16 different machine learning (ML) models of NHANES data, performed Mendelian randomization (MR) studies on disease phenotypes, dietary preferences, microbiome, blood-based markers, and integrated differential gene expression and expression quantitative trait loci (eQTL) data from multiple cohorts to identify factors associated with GC risk.
View Article and Find Full Text PDFUnderstanding and Preventing Advanced Gastric Cancer in Young Hispanic Patients.
Cancer Epidemiol Biomarkers Prev
January 2025
Keck School of Medicine, University of Southern California, Los Angeles, California.
The risk of gastric cancer among immigrants from countries where Helicobacter pylori is endemic greatly exceeds those born in the United States. Among patients in the Los Angeles safety-net health system, the risk of advanced and fatal gastric cancer is higher in Hispanic versus non-Hispanic patients. There is an urgent need to define whether this reflects concomitant illnesses, such as metabolic disease, occupational exposures, or differential access to H.
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