Objective: The aim of this study was to assess the value of radionuclide esophageal transit time (RET) in prediction of the results of pneumatic dilation in patients with achalasia.
Patients And Methods: Thirty patients (13 males) with a mean age of 37 +/- 15.6 years (range 17-73 years) were included in the study. All patients were diagnosed to have idiopathic achalasia of the cardia and selected for pneumatic dilation. Each patient had three RET, two the same day of dilation (pre-and postdilation) and a third follow up one within three months of dilation (4 patients failed to come for follow up and were excluded).
Results: Several parameters were derived from RET studies, T/50: time required for 50% of activity in the esophagus to be cleared, T/10 : time required for 90% of activity in the esophagus to be cleared and percentage clearance at 10 min. These parameters were compared to response of dysphagia to dilation. It was evident that the higher the esophageal clearance postdilation, the better the outcome. When immediate post dilation clearance was 85% or more the success rate was 83.3% whereas when it was 20-50% the success rate was only 21.4%. No relation was found between T/50, T/10 and dysphagia response.
Conclusion: RET appears to be a useful quantitative procedure in the assessment of pneumatic dilation outcome in achalasia patients.
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Orphanet J Rare Dis
January 2025
Department of Pediatric Gastroenterology and Nutrition, Amsterdam UMC, Emma Children's Hospital, Vrije Universiteit, Amsterdam, The Netherlands.
Background: Achalasia is a rare esophageal motility disorder with an estimated annual incidence of 1-5/100.000 and a mean age at diagnosis > 50 years of age. Only a fraction of the patients has an onset during childhood (estimated incidence of 0.
View Article and Find Full Text PDFWorld J Urol
January 2025
Department of Urology, Azienda Socio Sanitaria Territoriale Lariana, Como, Italy.
Purpose: To assess differences in safety and efficacy between 24 and 18 Fr pneumatic balloon dilators for percutaneous nephrolithotripsy (PCNL) of renal stones between 10 and 20 mm.
Methods: Patients were randomized to dilatation with a 24 Fr (Group A) versus 18 Fr (Group B) Ultraxx pneumatic dilator (Cook Medical). In all procedures percutaneous puncture was performed under ultrasound guidance.
Rev Gastroenterol Peru
January 2025
Universidad Peruana Cayetano Heredia, Lima, Perú.
We report the case of an elderly patient with progressive dysphagia to solids and later to liquids, and weight loss. The patient underwent an upper endoscopy, which showed multiple stenoses and trachealization. Biopsies were taken and a diagnosis of lymphocytic esophagitis was made.
View Article and Find Full Text PDFPhysiol Meas
January 2025
Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMETTyB), Universidad Favaloro-CONICET, Buenos Aires, Argentina.
Aortic dilatation is a severe pathology that increases the risk of rupture and its hemodynamics could be accurately assessed by using the 4D flow cardiovascular magnetic resonance (CMR) technique but flow assessment under complex flow patterns require validation. The aim of this work was to develop ansystem compatible with CMR to assess the accuracy of volume flow measurements in dilated aortas.Two latex models, one with ascending and the other with abdominal aortic aneurysms were manufactured to ensure a constant and controlled net flow volume along the aortic length.
View Article and Find Full Text PDFMed J Armed Forces India
December 2024
Consultant (Med & Gastroenterology), Command Hospital (Eastern Command), Kolkata, India.
Background: Achalasia is characterized by failure of relaxation of the lower oesophageal sphincter (LOS) and abnormal peristalsis during swallowing. The study aimed to observe the effects of intervention in three sub-types of achalasia and compare the intervention outcomes among the three sub-types.
Methods: Forty-one patients underwent Eckardt scoring for severity of achalasia, followed by high-resolution manometry (HRM).
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