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Genomic Epidemiology of 2023-2024 Oropouche Outbreak in Iquitos, Peru reveals independent origin from a concurrent outbreak in Brazil.
medRxiv
December 2024
Asociación Benéfica Prisma, Iquitos, Peru.
Oropouche virus is an arbovirus endemic to the Americas. Periodic outbreaks have occurred since its description in 1955. In late 2023, an outbreak occurred in Peru, centered in and around Iquitos in the Eastern Peruvian Amazon.
View Article and Find Full Text PDFSchmallenberg Virus, from the Necropsy Room to the Laboratory.
Methods Mol Biol
December 2024
Faculty of Veterinary Medicine, Department of Morphology and Pathology, FARAH Research Center, University of Liège, Liège, Belgium.
In a world facing significant climate changes, arboviruses are expanding into new regions. In recent decades, Western Europe has experienced multiple outbreaks of epizootic arboviruses in ruminants, including the Schmallenberg virus. This virus emerged in 2011 and spread rapidly across the continent, causing severe malformations in the central nervous systems of ruminant fetuses.
View Article and Find Full Text PDFA Review on Reliable and Standardized Animal Models to Study the Pathogenesis of Schmallenberg Virus in Ruminant Natural Host Species.
Methods Mol Biol
December 2024
Faculty of Veterinary Medicine, Research Unit of Epidemiology and Risk analysis applied to Veterinary sciences (UREAR-ULiège), Fundamental and Applied Research for Animal and Health (FARAH) Center, University of Liege, Liege, Belgium.
In the late summer of 2011, the Netherlands reported a cluster of reduced milk yield, fever, and diarrhea in dairy cattle. In March 2012, congenital malformations appeared, and Schmallenberg virus (SBV) was identified, becoming one of the few orthobunyaviruses distributed in Europe. Initially, little was known about the pathogenesis and epidemiology of these viruses in the European context, so assumptions were largely extrapolated from related viruses and other regions worldwide.
View Article and Find Full Text PDFOropouche virus: Understanding "sloth fever" disease dynamics and novel intervention strategies against this emerging neglected tropical disease.
Virulence
December 2024
Department of Veterinary & Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, Twin Cities, MN, USA.
Article Synopsis
- Oropouche virus (OROV) is an arbovirus that causes "sloth fever," transmitted mainly by midges in both rural and urban areas.
- Human infections can result in acute fever and, in severe cases, neurological issues, with over half a million people infected since its first detection in 1955.
- The absence of FDA-approved vaccines and treatments means current care focuses on supportive measures, highlighting the importance of developing vaccines to control outbreaks, especially as OROV risk increases with climate change and global travel.
We report a fatal case of Crimean-Congo hemorrhagic fever in Portugal. An 83-year-old man, initially suspected of having Mediterranean spotted fever, was later confirmed to have Crimean-Congo hemorrhagic fever by the detection of viral genome in the patient's serum and the presence of specific IgM antibodies.
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