Diet and nutritional factors play a large role in influencing both the quality and quantity of life after the diagnosis of cancer. The oncology nurse is well-positioned to: 1) help ensure that nutritional needs are met for patients who are newly diagnosed, undergoing active treatment, or have advanced disease; 2) facilitate referral of patients with more intensive nutritional needs to registered dietitians; and 3) promote the importance of weight management and a healthful plant-based diet, low in saturated fat and simple sugars, and high in fruits and vegetables and unrefined whole grains, to patients likely to join the ranks of an ever-expanding population of cancer survivors--who now constitute roughly 4% of the US population and number more than 11 million.
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Inflammation
December 2024
Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Intermittent fasting (IF) has been shown to ameliorate inflammation including DSS-induced colitis. It is well known that autophagy can limit inflammation and TFEB is a master transcriptional factor that regulates the processes of autophagy. However, whether TFEB is involved in the regulation of IF-mediated amelioration of inflammation and its mechanism remained unclear.
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December 2024
Department of Pathology, Renaissance School of Medicine, Stony Brook University, MART Building, 9M-0816, Lauterbur Dr., Stony Brook, NY 11794, USA.
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View Article and Find Full Text PDFMetabolites
December 2024
Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
ALDH1L1 plays a crucial role in folate metabolism, regulating the flow of one-carbon groups through the conversion of 10-formyltetrahydrofolate to tetrahydrofolate and CO in a NADP-dependent reaction. The downregulation of ALDH1L1 promotes malignant tumor growth, and silencing of ALDH1L1 is commonly observed in many cancers. In a previous study, knockout (KO) mice were found to have an altered liver metabotype, including significant alterations in glycine and serine.
View Article and Find Full Text PDFJ Fungi (Basel)
November 2024
School of Food and Health, Beijing Technology & Business University (BTBU), Beijing 100048, China.
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December 2024
Breast Center, São João University Hospital (ULS São João), 4200-319 Porto, Portugal.
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