AI Article Synopsis
- A 36-year-old jewelry producer experienced symptoms including tremors, slurred speech, lethargy, and coordination issues, likely due to mercury exposure.
- After treatment with 2,3-dimercapto-1-propanesulfonate, the patient showed significant clinical improvement and high levels of mercury excretion.
- The report suggests that this treatment should be considered for patients with symptoms related to mercury vapor exposure and confirmed diagnosis.
Article Abstract
Case Report: A 36-year-old jewelry producer presented with tremor, slurred speech, lethargy, headache, and incoordination. On examination he had a coarse tremor of the outstretched hands and protruded tongue, slurred speech, "Hatter's shakes" handwriting, impaired heel-toe walking and heel-shin coordination, mild dysdiadochokinesis, and constricted visual fields to confrontation. The patient received four 5-day courses of oral 2,3-dimercapto-1-propanesulfonate (30 mg/kg/day), which was associated with substantial objective clinical improvement and the excretion of 99,406 microg mercury.
Conclusion: We recommend that the administration of 2,3-dimercapto-1-propanesulfonate should be considered in symptomatic patients who have been exposed to mercury vapor and who have supporting analytical confirmation of the diagnosis.
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| http://dx.doi.org/10.3109/15563650903333812 | DOI Listing |
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