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An Automated Clinical Laboratory Decision Support System for Test Utilization, Medical Necessity Verification and Payment Processing.
Interact J Med Res
January 2025
University of California, San Francisco, Department of Laboratory Medicine, San Francisco, US.
Physicians could improve the efficiency of the healthcare system if a reliable resource were available to aid them in better understanding, selecting, and interpreting the diagnostic laboratory tests. It has been well established and widely recognized that (a) laboratory testing provides 70-85% of the objective data that physicians use in diagnosis and treatment of their patients, (b) orders for laboratory tests in the U.S.
View Article and Find Full Text PDFBlood Transfusions for Chronic Malaria Anemia in Prisoners of War on the Thai-Burma Railway 1943-1945.
Am J Trop Med Hyg
January 2025
Australian Defence Force Malaria and Infectious Disease Institute, Enoggera, Australia.
Allied prisoners of war (POWs) working on the Imperial Japanese Army's railroad from Thailand to Burma during 1943-1945 devised a blood transfusion service to rescue severely ill fellow prisoners who were otherwise unlikely to survive the war. Extant transfusion records (1,251 recipients, 1,189 donors) in ledger books held by the United Kingdom National Archives at Kew were accessed and analyzed. Survival to the end of the war in 1945 was determined from Commonwealth War Graves Commission records.
View Article and Find Full Text PDFThe Effects of a Low-Volume, High-Intensity Preseason Microcycle on Neuromuscular Performance in Collegiate Female Basketball Players.
J Strength Cond Res
December 2024
Jayhawk Athletic Performance Laboratory-Wu Tsai Human Performance Alliance, University of Kansas, University of Kansas, Lawrence, Kansas.
Philipp, NM, Blackburn, SD, Cabarkapa, D, and Fry, AC. The effects of a low-volume, high-intensity pre-season micro-cycle on neuromuscular performance in collegiate female basketball players. J Strength Cond Res 38(12): 2136-2146, 2024-The use of stretch-shortening cycle (SSC)-based measures of vertical jump performance to monitor responses to training exposures is common practice in sport science.
View Article and Find Full Text PDFLarge clones of Clonal Hematopoiesis affect outcome in Mantle Cell Lymphoma: Results from The FIL MCL0208 Clinical Trial.
Blood Adv
January 2025
Department of Molecular Biotechnologies and Health Sciences, University of Torino, Torino, Italy.
Although recent evidence suggests that myeloid clonal hematopoiesis (M-CH) may influence lymphoma clinical outcome, its impact in mantle cell lymphoma (MCL) remains unclear. Here, we report a comprehensive NGS-based analysis of the M-CH mutational landscape at baseline and follow-up in patients enrolled in the Fondazione Italiana Linfomi (FIL) MCL0208 phase 3 trial (NCT02354313), evaluating lenalidomide maintenance versus observation after chemoimmunotherapy and autologous stem cell transplantation (ASCT) in untreated young MCL patients. Overall, 254/300 (85%) enrolled patients (median age 57 years [32-66]) had a baseline sample available for CH analysis.
View Article and Find Full Text PDFRecruiting Young People for Digital Mental Health Research: Lessons From an AI-Driven Adaptive Trial.
J Med Internet Res
January 2025
Black Dog Institute, University of New South Wales, Sydney, Australia.
Background: With increasing adoption of remote clinical trials in digital mental health, identifying cost-effective and time-efficient recruitment methodologies is crucial for the success of such trials. Evidence on whether web-based recruitment methods are more effective than traditional methods such as newspapers, media, or flyers is inconsistent. Here we present insights from our experience recruiting tertiary education students for a digital mental health artificial intelligence-driven adaptive trial-Vibe Up.
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