Conclusions: Oxygen consumption by bacteria could be a cause of the negative middle ear pressure in ears with otitis media (OM).
Objective: To determine whether oxygen consumption by bacteria could be a cause for production of negative pressure in ears with OM.
Materials And Methods: Hermetically sealed bottles containing high dose (group A) and low dose (group B) of Streptococcus pneumoniae with air space and maintained at 37 degrees C in a water bath were connected to a micropressure sensor. The chronological pressure changes were monitored in vitro for 3-13 h and were compared with those in the control bottles containing culture medium only.
Results: The pressure of the group A samples showed significantly lower values than that of controls 3 h later (p<0.0001). In group B, the pressure was also significantly lower than that in the control group (p<0.0001). The partial pressures of oxygen measured at the beginning and end of the experiment in the six samples in group B showed significant decrease, while that in the control group showed only a slight decrease (p<0.0019).
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http://dx.doi.org/10.1080/00016480902933064 | DOI Listing |
Int J Biol Macromol
December 2024
College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, Zhejiang Province, PR China. Electronic address:
As the substrate, tobacco waste extract (TWE) can produce bacterial cellulose (BC), a biobased material. However, nicotine inhibits BC production (adding 0.8 g/L nicotine to the HS medium had a negative effect on BC synthesis) and needs to be removed.
View Article and Find Full Text PDFNat Commun
December 2024
Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
The mechanisms underlying the impact of probiotic supplementation on health remain largely elusive. While previous studies primarily focus on the discovery of novel bioactive bacteria and alterations in the microbiome environment to explain potential probiotic effects, our research delves into the role of living Lactiplantibacillus (formerly known as Lactobacillus) and their conditioned media, highlighting that only the former, not dead bacteria, enhance the healthspan of Caenorhabditis elegans (C. elegans).
View Article and Find Full Text PDFBioresour Technol
December 2024
College of Resources and Environment, Huazhong Agricultural University, Wuhan 430070, China. Electronic address:
Microalgal-bacteria biofilm shows great potential in low-cost greywater treatment. Accurately predicting treated greywater quality is of great significance for water reuse. In this work, machine learning models were developed for simulating and predicting linear alkylbenzene sulfonate (LAS) removal using 152-days collected data from a battled oxygenic microalgal-bacteria biofilm reactor (MBBfR).
View Article and Find Full Text PDFCJC Open
December 2024
Department of Cardiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China (USTC), Hefei, China.
Background: The aim of this study was to assess the impact of panvascular disease (PVD) on quality of life (QOL), exercise capacity, and clinical outcomes, in patients with heart failure (HF) with reduced ejection fraction (HFrEF).
Methods: We performed a post hoc analysis of the Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION; NCT00047437). Patients with PVD were defined as those having coronary heart disease, stroke, or peripheral vascular disease at baseline.
Am J Pathol
December 2024
Division of Gastroenterology and Hepatology, Stanford University, Palo Alto, California; Palo Alto VA, Palo Alto, California. Electronic address:
Mitochondrial maladaptation and dysfunction contribute to the progression of metabolic dysfunction-associated steatohepatitis (MASH). The authors recently implicated the induction of Shc in progressive MASH during aging and the cytoplasmic p52Shc isoform in the activation of redox enzyme NOX2. The mitochondrial Shc isoform p46Shc was shown to repress acetyl-coenzyme A acyltransferase 2 (ACAA2) in vitro.
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