Despite increased professionalization of adolescent sport and improved articulation to elite adult participation, the impact of sports such as rugby union among adolescents is under-explored. This study describes psychological stress-recovery responses relative to training loads in 106 male adolescent rugby union players. The results showed that players with the highest training and physical activity volumes during the season demonstrated more favourable recovery-stress states than moderate- and low-volume groups. Stress and under-recovery did not increase with increases in weekly volume when assessed across a season. When assessed more acutely during intensive competition phases, stress and under-recovery increased with increases in participation demands. Despite better psychological stress and recovery profiles of more elite, higher-load players, not all participants demonstrated favourable capacities to deal with stress and recovery processes. Seven participants were in at least two of three categories of highest volume, highest stress, and poorest recovery. Even in the absence of a full understanding of the impact of high-volume, high-stress, poor-recovery participation among adolescent athletes, these markers may be precursors for more deleterious outcomes such as injury, performance decrements, and overtraining. Findings support the efficacy of serially monitoring young athletes.
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http://dx.doi.org/10.1080/02640410903096611 | DOI Listing |
Acta Neuropathol Commun
December 2024
Institute of Physiology and Pathophysiology, Department of Cardiovascular Physiology, Heidelberg University, Heidelberg, Germany.
Severity and outcome of strokes following cerebral hypoperfusion are significantly influenced by stress responses of the blood vessels. In this context, brain endothelial cells (BEC) regulate inflammation, angiogenesis and the vascular resistance to rapidly restore perfusion. Despite the relevance of these responses for infarct volume and tissue recovery, their transcriptional control in BEC is not well characterized.
View Article and Find Full Text PDFJ Biol Chem
December 2024
Department of Cell and Molecular Physiology, Loyola University Chicago, Maywood, IL, USA. Electronic address:
The sarco(endo)plasmic reticulum Ca ATPase (SERCA) is a membrane transporter that creates and maintains intracellular Ca stores. In the heart, SERCA is regulated by an inhibitory interaction with the monomeric form of the transmembrane micropeptide phospholamban (PLB). PLB also forms avid homo-pentamers, and dynamic exchange of PLB between pentamers and SERCA is an important determinant of cardiac responsiveness to exercise.
View Article and Find Full Text PDFJ Control Release
December 2024
Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Department of Cardiology and Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China; Department of Cardiovascular Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China. Electronic address:
Myocardial ischemia-reperfusion (I/R) injury represents a significant clinical challenge with limited therapeutic options. Single-cell RNA sequencing and bioinformatics analyses have revealed complex cellular interactions within cardiac tissue, highlighting the crucial role of cardiomyocytes in intercellular communication. During I/R injury, cardiomyocytes experience severe endoplasmic reticulum (ER) stress, leading to detrimental intercellular communication that affects surrounding cells, particularly promoting the transformation of macrophages toward a pro-inflammatory phenotype.
View Article and Find Full Text PDFJ Biomech
December 2024
Department of Cardiology, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong 518033, China; Guangdong Innovative Engineering and Technology Research Center for Assisted Circulation, Sun Yat-sen University, Shenzhen, Guangdong 518033, China. Electronic address:
Enhanced external counterpulsation (EECP) is widely utilized in rehabilitating patients after percutaneous coronary intervention (PCI) and has demonstrated efficacy in promoting cardiovascular function recovery. Although the precise mechanisms of the therapeutic effects remain elusive, it is widely postulated that the improvement of biomechanical environment induced by EECP plays a critical role. This study aimed to unravel the underlying mechanism through a numerical investigation of the in-stent biomechanical environment during EECP using an advanced multi-dimensional 0/1D-3D coupled model.
View Article and Find Full Text PDFEcotoxicol Environ Saf
December 2024
College of Animal Science, Shanxi Agricultural University, Jinzhong 030800, China; Shanxi Key Laboratory of Animal Genetics Resource Utilization and Breeding, Jinzhong 030800, China. Electronic address:
Fish metabolism, growth, development, and physiological conditions are highly sensitive to fluctuations in water temperature. The Ussuri catfish (Pseudobagrus ussuriensis) is an important native economic species in China. However, research on heat stress in P.
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