Objective: Ossification of the ligamentum flavum (OLF) is a rare cause of thoracic myelopathy. The aim of this study was to identify factors associated with the surgical outcome on the basis of preoperative clinical and radiological findings.
Methods: Data obtained in 26 patients whot underwent posterior decompression for thoracic myelopathy, caused by thoracic OLF, were analyzed retrospectively. Patient age, duration of symptoms, OLF type, preoperative and postoperative neurological status using the Japanese Orthopedic Association (JOA) scoring system, surgical outcome, and other factors were reviewed. We compared the various factors and postoperative prognosis. All patients had undergone decompressive laminectomy and excision of the OLF.
Results: Using the JOA score, the functional improvement was excellent in 8 patients, good in 14, fair in 2, and unchanged in 2. A mean preoperative JOA score of 6.65 improved to 8.17 after an average of 27.3 months. According to our analysis, age, gender, duration of symptoms, the involved spinal level, coexisting spinal disorders, associated trauma, intramedullary signal change, and dural adhesions were not related to the surgical outcome. However, the preoperative JOA score and type of OLF were the most important predictors of the surgical outcome.
Conclusion: Early diagnosis and sufficient surgical decompression could improve the functional prognosis for thoracic OLF. The postoperative results were found to be significantly associated with the preoperative severity of myelopathy and type of OLF.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764014 | PMC |
http://dx.doi.org/10.3340/jkns.2009.46.3.189 | DOI Listing |
Eur J Vasc Endovasc Surg
March 2025
Department of Vascular and Endovascular Surgery, Manchester University NHS Foundation Trust, Manchester, UK; Division of Cardiovascular Sciences, School of Medical Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.
Objective: This systematic review aimed to assess clinical outcomes of branched endovascular aortic repair (BEVAR) with inner branches (iBEVAR) and inner/outer branches (oBEVAR).
Data Sources: A systematic literature review was performed using the electronic bibliographic databases MEDLINE, Embase, Scopus, Web of Science, and the Cochrane Library up to May 2024.
Review Methods: The review was designed and reported in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines.
Infect Drug Resist
March 2025
The Department of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.
Background: is a common opportunistic infection in patients with acquired immune deficiency syndrome (AIDS) in South China. Spinal cord abscesses caused by are exceptionally rare and present with non-specific symptoms, which may result in delayed diagnosis and heightened adverse prognoses.
Case Presentation: We report a case of a spinal cord abscess in a 30-year-old patient with AIDS that was caused by infection.
Zhen Ci Yan Jiu
February 2025
College of Chinese Medicine, Chongqing Medical University, Chongqing 400016, China.
Objectives: To observe the effect of electroacupuncture (EA) on neuroinflammatory response and glial scar formation Via regulating expression of neutrophil extracellular traps (NETs) in mice with spinal cord injury (SCI).
Methods: Sixty female C57BL/6 mice were randomized into sham operation, model, EA, DNase1 and EA+DNase1 groups, with 12 mice in each group. The SCI model was established by clamping the spinal cord with a serrefine after laminectomy at the 11 thoracic vertebra (T11).
Future Oncol
March 2025
xDepartment of Oncology, National Taiwan University Hospital and National Taiwan University Cancer Center, Taipei, Taiwan.
Annu Int Conf IEEE Eng Med Biol Soc
July 2024
This study aimed to determine an optimal model involving thoracic electrical impedance tomography (EIT) metrics and patient geometric information to best correlate to standard pulmonary function test (PFT) measures in a cohort of 32 ALS patients and 32 age-matched healthy controls. Thoracic EIT is a non-invasive technology in which an electrode belt chest allows for real-time impedance imaging of respiratory function. The optimal form of the model was determined via a genetic algorithm a novel technique for model generation in EIT applications.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!