In cardiac medicine, Dr. Michael Ellis DeBakey is the undisputed pioneer of this century, maybe even in history. The design of the ventricular assist device (VAD), the Dacron-created artificial blood vessel and his many other firsts revolutionized heart surgery (specifically aortic surgery) forever. In fact, his contributions were enormous and left and amazing legacy. DeBakey was known to have a temper and that he was a very difficult surgeon to work with. However, even his critics could not deny the impact he had on the world of medicine. In his early nineties, he still practiced surgery. DeBakey was a man that accomplished all he set out to do and died on early July 2008.
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http://dx.doi.org/10.1080/08941930903054743 | DOI Listing |
Nat Commun
January 2024
Drexel University/Tower Health Hospital, Philadelphia, PA, USA.
The glycosylation of IgG plays a critical role during human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, activating immune cells and inducing cytokine production. However, the role of IgM N-glycosylation has not been studied during human acute viral infection. The analysis of IgM N-glycosylation from healthy controls and hospitalized coronavirus disease 2019 (COVID-19) patients reveals increased high-mannose and sialylation that correlates with COVID-19 severity.
View Article and Find Full Text PDFJAMA Otolaryngol Head Neck Surg
May 2022
Department of Otorhinolaryngology, Ochsner Clinic Foundation, New Orleans, Louisiana.
Importance: Emerging computed tomographic (CT) imaging techniques for the localization of primary hyperparathyroidism (PHPT) may be superior to the current imaging standard, thus necessitating a critical review and pooling of available evidence.
Objective: Primary hyperparathyroidism requires accurate imaging to guide definitive surgical management. Advanced techniques including 4-dimensional computed tomographic (4D-CT) scan have been investigated over the past decade.
Chest
September 2021
Department of Medicine, University of Pittsburgh, Pittsburgh, PA. Electronic address:
Background: Smokers manifest varied phenotypes of pulmonary impairment.
Research Question: Which pulmonary phenotypes are associated with coronary artery disease (CAD) in smokers?
Study Design And Methods: We analyzed data from the University of Pittsburgh COPD Specialized Center for Clinically Oriented Research (SCCOR) cohort (n = 481) and the Genetic Epidemiology of COPD (COPDGene) cohort (n = 2,580). Participants were current and former smokers with > 10 pack-years of tobacco exposure.
Thorax
June 2021
Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Clin Neurol Neurosurg
January 2021
Department of Neurological Surgery, Ochsner Clinic Foundation, New Orleans, LA, United States. Electronic address:
Background: The "kissing carotids" (KCS) phenomenon refers to bilateral retropharyngeal displacement of the internal carotid arteries (ICA). This anomalous anatomy can impose a significant surgical challenge to spine surgeons.
Objective: In this report, we describe our approach for an anterior cervical discectomy and fusion in the setting of kissing carotids.
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